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Barinthus Biotherapeutics plc (BRNS)

Healthcare | Biotechnology | Germantown, United States | NasdaqCM
0.75 USD 0.00 (-0.493%) ⇩ (Aug. 28, 2026, 4 p.m. EDT)
After hours: 0.74 -0.01 (-0.006%) ⇩ (Aug. 28, 2026, 5:53 p.m. EDT)

Short-term:★★⯪☆☆Long-term:⯪☆☆☆☆Dividends:☆☆☆☆☆
Hot Take | Aug. 22, 2026, 3:32 a.m. EDT

The investment case here is fundamentally broken. The business has suffered a catastrophic multi-year decline, dropping nearly 92% over the last four years with every single year showing negative returns. This is not a temporary setback; it is a structural deterioration where the market has consistently reassessed the company's value downward. While the balance sheet currently shows low debt relative to equity, the massive negative cash flows and losses indicate a company burning through capital without generating returns. The recent price action shows a slight, fragile recovery, but the statistical forecast models predict further downside, confirming the lack of immediate momentum. With no dividend to provide income and a forward P/E that implies negative earnings, there is no safety margin for a long-term holder. The analyst price targets suggest a potential rebound, but given the depth of the decline and the continuous negative performance, this remains a high-risk speculative play rather than a viable investment.

Model Selection — Backtest MAE (log-scale, lower is better)
ModelMAE
AutoARIMA ✓0.122056
MSTL0.128763
AutoETS0.129107
AutoTheta0.149267

Forecast horizon: 45 days | Selected: AutoARIMA

Forecast Reliability
Score 46%
H-stat 1.88
Ljung-Box p 0.000
Jarque-Bera p 0.074
Excess Kurtosis 0.39
Attribute Value
Sector Healthcare
Debt to Equity Ratio 18.019
Market Cap 30,485,528
Forward P/E -0.66
Beta -0.39
Previous Name Vaccitech plc
Website https://www.barinthusbio.com

Info Dump

Attribute Value
52 Week Change -0.37681162
Address1 20,400 Century Boulevard
Address2 Suite 210
All Time High 17.99
All Time Low 0.512
Ask 0.72
Ask Size 2
Average Analyst Rating 1.0 - Strong Buy
Average Daily Volume10 Day 37,650
Average Daily Volume3 Month 78,446
Average Volume 78,446
Average Volume10Days 37,650
Beta -0.394
Bid 0.65
Bid Size 3
Book Value 1.397
City Germantown
Compensation As Of Epoch Date 1,767,139,200
Country United States
Crypto Tradeable 0
Currency USD
Current Price 0.7463
Current Ratio 5.539
Custom Price Alert Confidence HIGH
Date Short Interest 1,786,665,600
Day High 0.7464
Day Low 0.7
Debt To Equity 18.019
Display Name Barinthus Biotherapeutics
Earnings Timestamp End 1,754,569,800
Earnings Timestamp Start 1,754,569,800
Ebitda -31,244,000
Ebitda Margins 0.0
Enterprise To Ebitda 0.591
Enterprise Value -18,453,472
Eps Current Year -0.915
Eps Forward -1.135
Eps Trailing Twelve Months -1.04
Esg Populated 0
Exchange NCM
Exchange Data Delayed By 0
Exchange Timezone Name America/New_York
Exchange Timezone Short Name EDT
Fifty Day Average 0.6222
Fifty Day Average Change 0.12409997
Fifty Day Average Change Percent 0.1994535
Fifty Two Week Change Percent -37.681164
Fifty Two Week High 1.83
Fifty Two Week High Change -1.0837001
Fifty Two Week High Change Percent -0.5921858
Fifty Two Week Low 0.512
Fifty Two Week Low Change 0.23429996
Fifty Two Week Low Change Percent 0.45761707
Fifty Two Week Range 0.512 - 1.83
Financial Currency USD
First Trade Date Milliseconds 1,619,789,400,000
Float Shares 27,257,649
Forward Eps -1.135
Forward P E -0.65753305
Free Cashflow -6,171,375
Full Exchange Name NasdaqCM
Full Time Employees 14
Fullday Change -0.00370002
Fullday Change Percent -0.493336
Fullday Price 0.74
Gmt Off Set Milliseconds -14,400,000
Gross Margins 0.0
Gross Profits 8,594,000
Has Pre Post Market Data 1
Held Percent Insiders 0.1981
Held Percent Institutions 0.44068
Implied Shares Outstanding 40,848,893
Industry Biotechnology
Industry Disp Biotechnology
Industry Key biotechnology
Is Earnings Date Estimate 1
Language en-US
Last Fiscal Year End 1,767,139,200
Long Business Summary Barinthus Biotherapeutics plc, together with its subsidiaries, engages in the research, development, and commercialization of immunotherapies and vaccines in the United States and the United Kingdom. The company develops VTP-1000, an antigen-specific immune tolerance candidate, which is in Phase I clinical trial to restore immune non-responsiveness to gluten in patients with celiac disease; and VTP-300, an immunotherapy, which is in Phase II clinical trial for the treatment of chronic hepatitis B virus infection. It has a license agreement with Oxford University Innovation for the development and commercialization of products with thermo-responsive adjuvant scaffolds; and U.S. National Institutes of Health for the evaluation of synthetic and polymer-based vaccine technology to prevent infectious disease and treat cancer in animal models. The company was formerly known as Vaccitech plc and changed its name to Barinthus Biotherapeutics plc in November 2023. Barinthus Biotherapeutics plc was founded in 2016 and is based in Germantown, Maryland.
Long Name Barinthus Biotherapeutics plc
Market us_market
Market Cap 30,485,528
Market State CLOSED
Max Age 86,400
Message Board Id finmb_366057508
Most Recent Quarter 1,782,777,600
Name Change Date 2,026-08-28
Net Income To Common -41,767,000
Next Fiscal Year End 1,798,675,200
Non Diluted Market Cap 29,915,099
Number Of Analyst Opinions 1
Open 0.731
Operating Cashflow -26,425,000
Operating Margins 0.0
Payout Ratio 0.0
Phone 443 917 0966
Post Market Change -0.0062999725
Post Market Change Percent -0.8441609
Post Market Price 0.74
Post Market Time 1,787,954,037
Prev Name Vaccitech plc
Previous Close 0.75
Price Eps Current Year -0.81562835
Price Hint 4
Price To Book 0.53421617
Profit Margins 0.0
Quick Ratio 5.333
Quote Source Name Nasdaq Real Time Price
Quote Type EQUITY
Recommendation Key strong_buy
Recommendation Mean 1.0
Region US
Regular Market Change -0.003700018
Regular Market Change Percent -0.49333572
Regular Market Day High 0.7464
Regular Market Day Low 0.7
Regular Market Day Range 0.7 - 0.7464
Regular Market Open 0.731
Regular Market Previous Close 0.75
Regular Market Price 0.7463
Regular Market Time 1,787,947,200
Regular Market Volume 31,282
Return On Assets -0.18993
Return On Equity -0.52384996
Sand P52 Week Change 0.20504117
Sector Healthcare
Sector Disp Healthcare
Sector Key healthcare
Shares Outstanding 40,848,893
Shares Percent Shares Out 0.0002
Shares Short 9,037
Shares Short Previous Month Date 1,784,073,600
Shares Short Prior Month 29,440
Short Name Barinthus Biotherapeutics plc
Short Percent Of Float 0.0004
Short Ratio 0.25
Source Interval 15
State MD
Symbol BRNS
Target High Price 6.0
Target Low Price 6.0
Target Mean Price 6.0
Target Median Price 6.0
Total Cash 59,295,000
Total Cash Per Share 1.452
Total Debt 10,295,000
Tradeable 0
Trailing Annual Dividend Rate 0.0
Trailing Annual Dividend Yield 0.0
Trailing Eps -1.04
Trailing Peg Ratio None
Triggerable 1
Two Hundred Day Average 0.660145
Two Hundred Day Average Change 0.086155
Two Hundred Day Average Change Percent 0.13050921
Type Disp Equity
Volume 31,282
Website https://www.barinthusbio.com
Zip 20,874