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Avalo Therapeutics, Inc. (AVTX)

Healthcare | Biotechnology | Wayne, United States | NasdaqCM
14.29 USD -0.37 (-2.524%) ⇩ (April 21, 2026, 4 p.m. EDT)

Short-term:★★★★☆Long-term:★★☆☆☆Dividends:☆☆☆☆☆
Hot Take | April 19, 2026, 1:37 a.m. EDT

Avalo Therapeutics is exhibiting the classic 'biotech gamble' profile: deep technical distress balanced against aggressive institutional speculation on next-generation product data. The 240% drop from its 2023 highs and negative fundamentals make it a terrible permanent hold, but the options data screams 'momentum play' with speculative buyers betting all-in on a potential catalyst-driven rebound to avoid deep strikes. This is a binary event-driven trade, not an investment.

Model Selection — Backtest MAE (log-scale, lower is better)
ModelMAE
MSTL ✓0.080871
AutoTheta0.082146
AutoETS0.082305
AutoARIMA0.104199

Forecast horizon: 45 days | Selected: MSTL

Forecast Reliability
Score 60%
H-stat 1.96
Ljung-Box p 0.000
Jarque-Bera p 0.391
Excess Kurtosis -0.93
Attribute Value
Sector Healthcare
Debt to Equity Ratio 0.514
Revenue per Share 0.004
Market Cap 325,646,976
Forward P/E -4.71
Beta 0.94
Previous Name Cerecor Inc.
Website https://www.avalotx.com

As of April 19, 2026, 1:37 a.m. EDT: Options flow shows aggressive call buying with disproportionate Open Interest (OI) at strikes 22.5 (100+ contracts OI) and 30.0 (10k OI) for May and June expirations, suggesting a high-strike momentum target. Conversely, put activity is concentrated at deep strikes (10.0, strike 10 for May/June) with significant OI, indicating a defined downside risk zone near the technical lows. The put/call ratio is skewed towards calls in terms of directional bias, though overall volume suggests a high-risk/high-reward speculative setup rather than a stable accumulation phase.


Info Dump

Attribute Value
52 Week Change 1.8868687
Address1 1,500 Liberty Ridge Drive
Address2 Suite 321
All Time High 22,032.0
All Time Low 3.39
Ask 18.18
Ask Size 2
Average Analyst Rating 1.2 - Strong Buy
Average Daily Volume10 Day 789,070
Average Daily Volume3 Month 668,632
Average Volume 668,632
Average Volume10Days 789,070
Beta 0.944
Bid 10.45
Bid Size 2
Book Value 4.486
City Wayne
Compensation As Of Epoch Date 1,767,139,200
Country United States
Crypto Tradeable 0
Currency USD
Current Price 14.29
Current Ratio 8.136
Custom Price Alert Confidence HIGH
Date Short Interest 1,774,915,200
Day High 14.75
Day Low 14.12
Debt To Equity 0.514
Display Name Avalo Therapeutics
Earnings Timestamp End 1,755,261,000
Earnings Timestamp Start 1,754,915,400
Ebitda -72,581,000
Ebitda Margins 0.0
Enterprise To Ebitda -3.138
Enterprise To Revenue 3,859.966
Enterprise Value 227,737,984
Eps Current Year -3.23667
Eps Forward -3.03333
Eps Trailing Twelve Months -5.84
Esg Populated 0
Exchange NCM
Exchange Data Delayed By 0
Exchange Timezone Name America/New_York
Exchange Timezone Short Name EDT
Fifty Day Average 15.3488
Fifty Day Average Change -1.0587997
Fifty Day Average Change Percent -0.06898258
Fifty Two Week Change Percent 188.68687
Fifty Two Week High 20.72
Fifty Two Week High Change -6.4299994
Fifty Two Week High Change Percent -0.31032816
Fifty Two Week Low 3.39
Fifty Two Week Low Change 10.9
Fifty Two Week Low Change Percent 3.215339
Fifty Two Week Range 3.39 - 20.72
Financial Currency USD
First Trade Date Milliseconds 1,444,829,400,000
Float Shares 20,144,536
Forward Eps -3.03333
Forward P E -4.7109942
Free Cashflow -17,263,124
Full Exchange Name NasdaqCM
Full Time Employees 33
Gmt Off Set Milliseconds -14,400,000
Gross Margins 0.0
Gross Profits -35,287,000
Has Pre Post Market Data 1
Held Percent Insiders 0.02577
Held Percent Institutions 0.84669
Implied Shares Outstanding 22,788,452
Industry Biotechnology
Industry Disp Biotechnology
Industry Key biotechnology
Is Earnings Date Estimate 1
Language en-US
Last Fiscal Year End 1,767,139,200
Last Split Date 1,703,808,000
Last Split Factor 1:240
Long Business Summary Avalo Therapeutics, Inc., a clinical stage biotechnology company, develops IL-1ß-based treatments for immune-mediated inflammatory diseases in the Unites States. Its lead product includes AVTX-009, a humanized monoclonal antibody that binds to interleukin-1ß, which is in phase 2 clinical trial to treat inflammatory diseases. The company was formerly known as Cerecor Inc. and changed its name to Avalo Therapeutics, Inc. in August 2021. Avalo Therapeutics, Inc. was incorporated in 2011 and is headquartered in Wayne, Pennsylvania.
Long Name Avalo Therapeutics, Inc.
Market us_market
Market Cap 325,646,976
Market State PRE
Max Age 86,400
Message Board Id finmb_145313032
Most Recent Quarter 1,767,139,200
Name Change Date 2,026-04-20
Net Income To Common -78,259,000
Next Fiscal Year End 1,798,675,200
Non Diluted Market Cap 325,874,863
Number Of Analyst Opinions 11
Open 14.75
Operating Cashflow -51,458,000
Operating Margins -334.61017
Payout Ratio 0.0
Phone 410 522 8707
Pre Market Change 0.0
Pre Market Change Percent 0.0
Pre Market Price 14.29
Pre Market Time 1,776,844,806
Prev Name Cerecor Inc.
Previous Close 14.66
Price Eps Current Year -4.4150314
Price Hint 2
Price To Book 3.1854658
Price To Sales Trailing12 Months 5,519.4404
Profit Margins 0.0
Quick Ratio 7.599
Quote Source Name Nasdaq Real Time Price
Quote Type EQUITY
Recommendation Key strong_buy
Recommendation Mean 1.15385
Region US
Regular Market Change -0.37
Regular Market Change Percent -2.52387
Regular Market Day High 14.75
Regular Market Day Low 14.12
Regular Market Day Range 14.12 - 14.75
Regular Market Open 14.75
Regular Market Previous Close 14.66
Regular Market Price 14.29
Regular Market Time 1,776,801,601
Regular Market Volume 674,422
Return On Assets -0.34117
Return On Equity -0.72435
Revenue Growth -0.693
Revenue Per Share 0.004
Sand P52 Week Change 0.3140242
Sector Healthcare
Sector Disp Healthcare
Sector Key healthcare
Shares Outstanding 22,788,452
Shares Percent Shares Out 0.2432
Shares Short 5,542,400
Shares Short Previous Month Date 1,772,150,400
Shares Short Prior Month 3,681,926
Short Name Avalo Therapeutics, Inc.
Short Percent Of Float 0.2441
Short Ratio 6.85
Source Interval 15
State PA
Symbol AVTX
Target High Price 52.0
Target Low Price 24.0
Target Mean Price 40.09091
Target Median Price 40.0
Total Cash 98,336,000
Total Cash Per Share 4.315
Total Debt 427,000
Total Revenue 59,000
Tradeable 0
Trailing Annual Dividend Rate 0.0
Trailing Annual Dividend Yield 0.0
Trailing Eps -5.84
Trailing Peg Ratio None
Triggerable 1
Two Hundred Day Average 13.8845
Two Hundred Day Average Change 0.4055004
Two Hundred Day Average Change Percent 0.029205259
Type Disp Equity
Volume 674,422
Website https://www.avalotx.com
Zip 19,087