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Assembly Biosciences, Inc. (ASMB)

Healthcare | Biotechnology | South San Francisco, United States | NasdaqGS
26.96 USD -0.44 (-1.606%) ⇩ (July 13, 2026, 4 p.m. EDT)
After hours: 26.96

Short-term:★★⯪☆☆Long-term:★☆☆☆☆Dividends:☆☆☆☆☆
Hot Take | July 11, 2026, 4:21 a.m. EDT

The long-term investment case is severely compromised by deteriorating fundamentals. Revenue has contracted by nearly 13%, and the company is burning cash with negative operating margins and a trailing P/E of over 340, signaling that the market views the current valuation as unjustified given the lack of profitability. While the price recently recovered slightly to close near the 50-day average, the multi-year trajectory remains deeply distressed, having lost three-quarters of its value over the last nine years. The recent $100 million capital raise highlights the company's desperate need for liquidity to fund its pipeline, further eroding shareholder value. On the short-term front, the stock is technically neutral; it is hovering around its 50-day moving average with no clear momentum catalyst to drive a breakout, despite the heavy options positioning at higher strikes which may act as resistance. With no dividend to provide income and a balance sheet showing significant free cash flow outflows, there is no safety net for investors. The statistical forecast offers no directional guidance, reinforcing the view that the immediate outlook is stagnant.

Model Selection — Backtest MAE (log-scale, lower is better)
ModelMAE
AutoTheta ✓0.080849
MSTL0.082365
AutoETS0.082919
AutoARIMA0.096191

Forecast horizon: 45 days | Selected: AutoTheta

Forecast Reliability
Score 43%
H-stat 0.55
Ljung-Box p 0.000
Jarque-Bera p 0.306
Excess Kurtosis -1.03
Attribute Value
Sector Healthcare
Debt to Equity Ratio 1.254
Revenue per Share 5.243
Market Cap 534,273,056
Trailing P/E 337.00
Forward P/E -12.81
Beta 1.08
Profit Margins -8.98%
Website https://www.assemblybio.com

As of July 11, 2026, 4:21 a.m. EDT: Speculators are positioning for significant volatility rather than a specific directional breakout. Call Open Interest is heavily concentrated at strikes 40 and 45, suggesting a belief in a potential rally to the upper end of the range, while Put Open Interest clusters at 22.5 and 30, creating a 'strangle' scenario where traders bet on a move away from the current price. The implied volatility is elevated for near-term expirations, indicating fear of a sharp swing in either direction.


Info Dump

Attribute Value
52 Week Change 0.4543525
Address1 Two Tower Place
Address2 7th Floor
All Time High 1,260.0
All Time Low 7.68
Ask 34.32
Ask Size 2
Audit Risk 8
Average Daily Volume10 Day 332,030
Average Daily Volume3 Month 201,714
Average Volume 201,714
Average Volume10Days 332,030
Beta 1.083
Bid 19.59
Bid Size 2
Board Risk 5
Book Value 12.497
City South San Francisco
Compensation As Of Epoch Date 1,767,139,200
Compensation Risk 5
Country United States
Crypto Tradeable 0
Currency USD
Current Price 26.96
Current Ratio 6.647
Custom Price Alert Confidence HIGH
Date Short Interest 1,782,777,600
Day High 27.395
Day Low 26.27
Debt To Equity 1.254
Display Name Assembly Biosciences
Earnings Timestamp End 1,754,942,400
Earnings Timestamp Start 1,754,510,400
Ebitda -13,425,000
Ebitda Margins -0.18882999
Enterprise To Ebitda -15.222
Enterprise To Revenue 2.874
Enterprise Value 204,354,704
Eps Current Year 0.14
Eps Forward -2.105
Eps Trailing Twelve Months 0.08
Esg Populated 0
Exchange NMS
Exchange Data Delayed By 0
Exchange Timezone Name America/New_York
Exchange Timezone Short Name EDT
Fifty Day Average 26.7824
Fifty Day Average Change 0.17759895
Fifty Day Average Change Percent 0.0066311816
Fifty Two Week Change Percent 45.43525
Fifty Two Week High 39.71
Fifty Two Week High Change -12.75
Fifty Two Week High Change Percent -0.32107782
Fifty Two Week Low 16.9
Fifty Two Week Low Change 10.059999
Fifty Two Week Low Change Percent 0.5952663
Fifty Two Week Range 16.9 - 39.71
Financial Currency USD
First Trade Date Milliseconds 1,292,596,200,000
Float Shares 8,802,439
Forward Eps -2.105
Forward P E -12.8076
Free Cashflow -16,556,875
Full Exchange Name NasdaqGS
Full Time Employees 73
Gmt Off Set Milliseconds -14,400,000
Governance Epoch Date 1,782,864,000
Gross Margins 0.0877
Gross Profits 6,235,000
Has Pre Post Market Data 1
Held Percent Insiders 0.28415
Held Percent Institutions 0.48438
Implied Shares Outstanding 19,817,250
Industry Biotechnology
Industry Disp Biotechnology
Industry Key biotechnology
Is Earnings Date Estimate 1
Language en-US
Last Fiscal Year End 1,767,139,200
Last Split Date 1,707,696,000
Last Split Factor 1:12
Long Business Summary Assembly Biosciences, Inc., a biotechnology company, develops therapeutic candidates for the treatment of viral diseases worldwide. Its pipeline includes long-acting helicase-primase inhibitors candidates, including ABI-5366 and ABI-1179, which are in Phase 1 clinical studies for recurrent genital herpes; and ABI-6250, an orally bioavailable hepatitis delta virus entry inhibitor that is in Phase 1a clinical study for the treatment of chronic hepatitis delta virus (HDV) infection. The company also develops ABI-4334, an orally bioavailable next generation capsid assembly modulator that is in Phase 1b study clinical trial for the treatment of chronic hepatitis B virus (HBV) infection; and ABI-7272, an oral broad-spectrum NNPI for the treatment of transplant-associated herpesviruses. It has an option, license, and collaboration agreement with Gilead Sciences, Inc. for the research and development of virology therapies. The company was formerly known as Ventrus Biosciences, Inc. and changed its name to Assembly Biosciences, Inc. in June 2014. Assembly Biosciences, Inc. was incorporated in 2005 and is headquartered in South San Francisco, California.
Long Name Assembly Biosciences, Inc.
Market us_market
Market Cap 534,273,056
Market State POSTPOST
Max Age 86,400
Message Board Id finmb_99715344
Most Recent Quarter 1,774,915,200
Net Income To Common -6,383,000
Next Fiscal Year End 1,798,675,200
Non Diluted Market Cap 542,992,650
Number Of Analyst Opinions 4
Open 27.04
Operating Cashflow -39,751,000
Operating Margins -1.38439
Overall Risk 4
Payout Ratio 0.0
Phone 833 509 4583
Post Market Change 0.0
Post Market Change Percent 0.0
Post Market Price 26.96
Post Market Time 1,783,973,404
Previous Close 27.4
Price Eps Current Year 192.57143
Price Hint 2
Price To Book 2.1573176
Price To Sales Trailing12 Months 7.514706
Profit Margins -0.089779995
Quick Ratio 6.516
Quote Source Name Nasdaq Real Time Price
Quote Type EQUITY
Recommendation Key none
Region US
Regular Market Change -0.440001
Regular Market Change Percent -1.60584
Regular Market Day High 27.395
Regular Market Day Low 26.27
Regular Market Day Range 26.27 - 27.395
Regular Market Open 27.04
Regular Market Previous Close 27.4
Regular Market Price 26.96
Regular Market Time 1,783,972,801
Regular Market Volume 112,985
Return On Assets -0.050619997
Return On Equity -0.056550004
Revenue Growth -0.128
Revenue Per Share 5.243
Sand P52 Week Change 0.20847368
Sector Healthcare
Sector Disp Healthcare
Sector Key healthcare
Share Holder Rights Risk 2
Shares Outstanding 19,817,250
Shares Percent Shares Out 0.12149999
Shares Short 2,407,951
Shares Short Previous Month Date 1,780,012,800
Shares Short Prior Month 1,683,891
Short Name Assembly Biosciences, Inc.
Short Percent Of Float 0.16319999
Short Ratio 8.54
Source Interval 15
State CA
Symbol ASMB
Target High Price 62.0
Target Low Price 43.0
Target Mean Price 50.0
Target Median Price 47.5
Total Cash 226,600,992
Total Cash Per Share 14.258
Total Debt 2,491,000
Total Revenue 71,097,000
Tradeable 0
Trailing Annual Dividend Rate 0.0
Trailing Annual Dividend Yield 0.0
Trailing Eps 0.08
Trailing P E 337.0
Trailing Peg Ratio None
Triggerable 1
Two Hundred Day Average 29.1874
Two Hundred Day Average Change -2.2274017
Two Hundred Day Average Change Percent -0.07631381
Type Disp Equity
Volume 112,985
Website https://www.assemblybio.com
Zip 94,080