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Aptevo Therapeutics Inc. (APVO)

Healthcare | Biotechnology | Seattle, United States | NasdaqCM
2.37 USD -0.06 (-2.273%) ⇩ (Aug. 28, 2026, 4 p.m. EDT)
After hours: 2.43 +0.07 (2.748%) ⇧ (Aug. 28, 2026, 7:35 p.m. EDT)

Short-term:★☆☆☆☆Long-term:⯪☆☆☆☆Dividends:☆☆☆☆☆
Hot Take | Aug. 22, 2026, 5:30 a.m. EDT

The immediate outlook is severely clouded by a brutal price collapse, with the stock tumbling nearly 99% over the last decade and suffering four consecutive years of negative annual returns. While the recent 14-day price action shows a brief, fragile bounce off the lows, the massive gap between the current price and the 50-day average suggests significant distribution pressure remains. The statistical forecast offers no directional edge, reflecting the chaotic nature of such a distressed asset. Fundamentally, the company is in deep distress: it reports massive losses, negative free cash flow, and a forward P/E that implies no earnings visibility. Although the balance sheet currently holds some cash relative to debt, the relentless burn rate and lack of profitability make survival uncertain without a miracle catalyst. With no dividend to provide income and a business model that has failed to generate value for investors over the long term, this security represents a speculative gamble rather than an investment opportunity.

Model Selection — Backtest MAE (log-scale, lower is better)
ModelMAE
AutoTheta ✓0.193906
AutoARIMA0.196461
AutoETS0.206506
MSTL0.209960

Forecast horizon: 45 days | Selected: AutoTheta

Forecast Reliability
Score 27%
H-stat 51.29
Ljung-Box p 0.000
Jarque-Bera p 0.014
Excess Kurtosis -0.47
Attribute Value
Sector Healthcare
Debt to Equity Ratio 69.674
Market Cap 4,261,659
Trailing P/E 0.01
Forward P/E -0.23
Beta 1.65
Website https://aptevotherapeutics.com

Info Dump

Attribute Value
52 Week Change -0.91597223
Address1 2,401 4th Avenue
Address2 Suite 1050
All Time High 68,020,448.0
All Time Low 2.301
Ask 2.99
Ask Size 2
Average Analyst Rating 1.0 - Strong Buy
Average Daily Volume10 Day 70,810
Average Daily Volume3 Month 56,911
Average Volume 56,911
Average Volume10Days 70,810
Beta 1.646
Bid 1.78
Bid Size 2
Book Value 4.257
City Seattle
Compensation As Of Epoch Date 1,767,139,200
Country United States
Crypto Tradeable 0
Currency USD
Current Price 2.365
Current Ratio 2.081
Custom Price Alert Confidence HIGH
Date Short Interest 1,786,665,600
Day High 2.46
Day Low 2.32
Debt To Equity 69.674
Display Name Aptevo Therapeutics
Dividend Date 1,585,267,200
Earnings Timestamp End 1,754,915,400
Earnings Timestamp Start 1,754,483,400
Ebitda -26,689,000
Ebitda Margins 0.0
Enterprise To Ebitda 0.05
Enterprise Value -1,326,341
Eps Current Year -16.02
Eps Forward -10.4
Eps Trailing Twelve Months 456.62
Esg Populated 0
Exchange NCM
Exchange Data Delayed By 0
Exchange Timezone Name America/New_York
Exchange Timezone Short Name EDT
Fax 206 838 0503
Fifty Day Average 3.99292
Fifty Day Average Change -1.6279199
Fifty Day Average Change Percent -0.4077016
Fifty Two Week Change Percent -91.59722
Fifty Two Week High 48.78
Fifty Two Week High Change -46.414997
Fifty Two Week High Change Percent -0.951517
Fifty Two Week Low 2.301
Fifty Two Week Low Change 0.06399989
Fifty Two Week Low Change Percent 0.027813945
Fifty Two Week Range 2.301 - 48.78
Financial Currency USD
First Trade Date Milliseconds 1,469,021,400,000
Float Shares 1,696,320
Forward Eps -10.4
Forward P E -0.22740385
Free Cashflow -15,564,750
Full Exchange Name NasdaqCM
Full Time Employees 33
Fullday Change -0.0550001
Fullday Change Percent -2.27273
Fullday Price 2.43
Gmt Off Set Milliseconds -14,400,000
Gross Margins 0.0
Has Pre Post Market Data 1
Held Percent Insiders 0.05717
Held Percent Institutions 0.028970001
Implied Shares Outstanding 1,801,970
Industry Biotechnology
Industry Disp Biotechnology
Industry Key biotechnology
Is Earnings Date Estimate 1
Language en-US
Last Fiscal Year End 1,767,139,200
Last Split Date 1,767,052,800
Last Split Factor 1:18
Long Business Summary Aptevo Therapeutics Inc., a clinical-stage research and development biotechnology company, focuses on developing immunotherapeutic candidates for the treatment of various forms of cancer in the United States. The company develops its products using ADAPTIR and ADAPTIR-FLEX platforms to generate monospecific, bispecific, and multi-specific antibody candidates capable of enhancing the human immune system against cancer cells. Its lead clinical blood cancer candidate is mipletamig that is in Phase 1b/2 clinical trial for the treatment of acute myelogenous leukemia. The company also develops ALG.APV-527, a novel investigational bispecific ADAPTIR candidate that is in Phase 1 clinical trial for the treatment malignant pleural mesothelioma, non-small cell lung, gastric/gastro-esophageal, head and neck squamous cell carcinoma, pancreatic, renal, ovarian, prostate, breast, cervical, colorectal, endometrial, and bladder cancers; APVO603, a preclinical dual agonist bispecific ADAPTIR candidate to treat multiple solid tumors; APVO442, a preclinical bispecific candidate based on the ADAPTIR-FLEX platform technology for the treatment of multiple solid tumors; and APVO711, a preclinical dual mechanism bispecific ADAPTIR candidate to treat prostate cancer. It has a collaboration and option agreement with Alligator Bioscience AB to develop ALG.APV-527. Aptevo Therapeutics Inc. was incorporated in 2016 and is headquartered in Seattle, Washington.
Long Name Aptevo Therapeutics Inc.
Market us_market
Market Cap 4,261,659
Market State CLOSED
Max Age 86,400
Message Board Id finmb_331280020
Most Recent Quarter 1,782,777,600
Net Income To Common -26,505,000
Next Fiscal Year End 1,798,675,200
Non Diluted Market Cap 4,360,767
Number Of Analyst Opinions 2
Open 2.46
Operating Cashflow -25,343,000
Operating Margins 0.0
Payout Ratio 0.0
Phone 206 838 0500
Post Market Change 0.06500006
Post Market Change Percent 2.748417
Post Market Price 2.43
Post Market Time 1,787,960,105
Previous Close 2.42
Price Eps Current Year -0.14762796
Price Hint 4
Price To Book 0.5555556
Profit Margins 0.0
Quick Ratio 1.888
Quote Source Name Nasdaq Real Time Price
Quote Type EQUITY
Recommendation Key strong_buy
Recommendation Mean 1.0
Region US
Regular Market Change -0.055000067
Regular Market Change Percent -2.2727299
Regular Market Day High 2.46
Regular Market Day Low 2.32
Regular Market Day Range 2.32 - 2.46
Regular Market Open 2.46
Regular Market Previous Close 2.42
Regular Market Price 2.365
Regular Market Time 1,787,947,200
Regular Market Volume 20,992
Return On Assets -1.11494
Return On Equity -4.20342
Sand P52 Week Change 0.20504117
Sector Healthcare
Sector Disp Healthcare
Sector Key healthcare
Shares Outstanding 1,801,970
Shares Percent Shares Out 0.0454
Shares Short 81,745
Shares Short Previous Month Date 1,784,073,600
Shares Short Prior Month 137,249
Short Name Aptevo Therapeutics Inc.
Short Percent Of Float 0.0454
Short Ratio 2.78
Source Interval 15
State WA
Symbol APVO
Target High Price 30.0
Target Low Price 21.0
Target Mean Price 25.5
Target Median Price 25.5
Total Cash 9,797,000
Total Cash Per Share 5.437
Total Debt 4,209,000
Tradeable 0
Trailing Annual Dividend Rate 0.0
Trailing Annual Dividend Yield 0.0
Trailing Eps 456.62
Trailing P E 0.0051793614
Trailing Peg Ratio None
Triggerable 1
Two Hundred Day Average 8.136435
Two Hundred Day Average Change -5.771435
Two Hundred Day Average Change Percent -0.70933217
Type Disp Equity
Volume 20,992
Website https://aptevotherapeutics.com
Zip 98,121