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Aptevo Therapeutics Inc. (APVO)

Healthcare | Biotechnology | Seattle, United States | NasdaqCM
5.28 USD -0.33 (-5.882%) ⇩ (April 17, 2026, 4 p.m. EDT)
After hours: 5.38 +0.10 (1.896%) ⇧ (April 17, 2026, 6:05 p.m. EDT)

Short-term: ★☆☆☆☆ | Long-term: ☆☆☆☆☆ | Dividends: ☆☆☆☆☆
Hot Take | April 11, 2026, 2:46 p.m. EDT

APVO is a highly volatile biotech stock with a significant negative price momentum, as evidenced by its recent price declines and the negative forward and trailing EPS. The stock has been affected by negative news, including a reverse split and disappointing trial results, which have contributed to its low valuation. The short-term forecasting model indicates a substantial price drop, suggesting a lack of momentum and potential for further losses. Long-term fundamentals are weak, with poor financial metrics and a low price-to-book ratio, making it a risky investment. There are no dividend payouts, which adds to the risk profile. Overall, this stock is not recommended for either short-term or long-term investment.

Model Selection — Backtest MAE (log-scale, lower is better)
ModelMAE
AutoARIMA ✓0.213251
AutoTheta0.266661
AutoETS0.396018
MSTL0.437441

Forecast horizon: 45 days | Selected: AutoARIMA

Forecast Reliability
Score 39%
H-stat 15.11
Ljung-Box p 0.000
Jarque-Bera p 0.045
Excess Kurtosis 0.84
Attribute Value
Sector Healthcare
Debt to Equity Ratio 26.633
Market Cap 6,239,513
Forward P/E -0.28
Beta 1.51
Website https://aptevotherapeutics.com

Info Dump

Attribute Value
52 Week Change -0.9769392
Address1 2,401 4th Avenue
Address2 Suite 1050
All Time High 68,020,448.0
All Time Low 3.8
Ask 6.89
Ask Size 2
Average Daily Volume10 Day 25,950
Average Daily Volume3 Month 58,740
Average Volume 58,740
Average Volume10Days 25,950
Beta 1.508
Bid 3.98
Bid Size 2
Book Value 17.419
City Seattle
Compensation As Of Epoch Date 1,767,139,200
Country United States
Crypto Tradeable 0
Currency USD
Current Price 5.28
Current Ratio 3.815
Custom Price Alert Confidence HIGH
Date Short Interest 1,774,915,200
Day High 5.6931
Day Low 5.261
Debt To Equity 26.633
Display Name Aptevo Therapeutics
Dividend Date 1,585,267,200
Earnings Timestamp End 1,754,915,400
Earnings Timestamp Start 1,754,483,400
Ebitda -26,072,000
Ebitda Margins 0.0
Enterprise To Ebitda 0.412
Enterprise Value -10,750,492
Eps Current Year -20.99
Eps Forward -18.65
Eps Trailing Twelve Months -87.27
Esg Populated 0
Exchange NCM
Exchange Data Delayed By 0
Exchange Timezone Name America/New_York
Exchange Timezone Short Name EDT
Fax 206 838 0503
Fifty Day Average 5.5418
Fifty Day Average Change -0.2617998
Fifty Day Average Change Percent -0.047240935
Fifty Two Week Change Percent -97.693924
Fifty Two Week High 486.0
Fifty Two Week High Change -480.72
Fifty Two Week High Change Percent -0.9891358
Fifty Two Week Low 3.8
Fifty Two Week Low Change 1.4800003
Fifty Two Week Low Change Percent 0.38947377
Fifty Two Week Range 3.8 - 486.0
Financial Currency USD
First Trade Date Milliseconds 1,469,021,400,000
Float Shares 1,180,969
Forward Eps -18.65
Forward P E -0.28310993
Free Cashflow -15,881,000
Full Exchange Name NasdaqCM
Full Time Employees 33
Gmt Off Set Milliseconds -14,400,000
Gross Margins 0.0
Has Pre Post Market Data 1
Held Percent Insiders 0.00064000004
Held Percent Institutions 0.018760001
Implied Shares Outstanding 1,181,726
Industry Biotechnology
Industry Disp Biotechnology
Industry Key biotechnology
Is Earnings Date Estimate 1
Language en-US
Last Fiscal Year End 1,767,139,200
Last Split Date 1,767,052,800
Last Split Factor 1:18
Long Business Summary Aptevo Therapeutics Inc., a clinical-stage research and development biotechnology company, focuses on developing immunotherapeutic candidates for the treatment of various forms of cancer in the United States. The company develops its products using ADAPTIR and ADAPTIR-FLEX platforms to generate monospecific, bispecific, and multi-specific antibody candidates capable of enhancing the human immune system against cancer cells. Its lead clinical blood cancer candidate is mipletamig that is in Phase 1b/2 clinical trial for the treatment of acute myelogenous leukemia. The company also develops ALG.APV-527, a novel investigational bispecific ADAPTIR candidate that is in Phase 1 clinical trial for the treatment of non-small cell lung cancer, head and neck, colorectal, pancreatic, breast, and other solid tumors; APVO603, a preclinical dual agonist bispecific ADAPTIR candidate to treat multiple solid tumors; APVO442, a preclinical bispecific candidate based on the ADAPTIR-FLEX platform technology for the treatment of multiple solid tumors; and APVO711, a preclinical dual mechanism bispecific ADAPTIR candidate to treat prostate cancer. It has a collaboration and option agreement with Alligator Bioscience AB to develop ALG.APV-527. Aptevo Therapeutics Inc. was incorporated in 2016 and is headquartered in Seattle, Washington.
Long Name Aptevo Therapeutics Inc.
Market us_market
Market Cap 6,239,513
Market State CLOSED
Max Age 86,400
Message Board Id finmb_331280020
Most Recent Quarter 1,767,139,200
Net Income To Common -25,967,000
Next Fiscal Year End 1,798,675,200
Non Diluted Market Cap 6,239,508
Number Of Analyst Opinions 1
Open 5.6
Operating Cashflow -25,592,000
Operating Margins 0.0
Payout Ratio 0.0
Phone 206 838 0500
Post Market Change 0.10009956
Post Market Change Percent 1.895825
Post Market Price 5.3801
Post Market Time 1,776,463,501
Previous Close 5.61
Price Eps Current Year -0.25154838
Price Hint 2
Price To Book 0.30311728
Profit Margins 0.0
Quick Ratio 3.573
Quote Source Name Nasdaq Real Time Price
Quote Type EQUITY
Recommendation Key none
Region US
Regular Market Change -0.33
Regular Market Change Percent -5.88235
Regular Market Day High 5.6931
Regular Market Day Low 5.261
Regular Market Day Range 5.261 - 5.6931
Regular Market Open 5.6
Regular Market Previous Close 5.61
Regular Market Price 5.28
Regular Market Time 1,776,456,000
Regular Market Volume 22,618
Return On Assets -0.76873
Return On Equity -2.3461301
Sand P52 Week Change 0.38150132
Sector Healthcare
Sector Disp Healthcare
Sector Key healthcare
Shares Outstanding 1,181,725
Shares Percent Shares Out 0.1126
Shares Short 133,103
Shares Short Previous Month Date 1,772,150,400
Shares Short Prior Month 116,763
Short Name Aptevo Therapeutics Inc.
Short Percent Of Float 0.11270001
Short Ratio 1.51
Source Interval 15
State WA
Symbol APVO
Target High Price 21.0
Target Low Price 21.0
Target Mean Price 21.0
Target Median Price 21.0
Total Cash 21,619,000
Total Cash Per Share 18.294
Total Debt 4,629,000
Tradeable 0
Trailing Annual Dividend Rate 0.0
Trailing Annual Dividend Yield 0.0
Trailing Eps -87.27
Trailing Peg Ratio None
Triggerable 1
Two Hundred Day Average 22.56198
Two Hundred Day Average Change -17.281979
Two Hundred Day Average Change Percent -0.7659779
Type Disp Equity
Volume 22,618
Website https://aptevotherapeutics.com
Zip 98,121