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Aptevo Therapeutics Inc. (APVO)

Healthcare | Biotechnology | Seattle, United States | NasdaqCM
4.15 USD +0.21 (5.330%) ⇧ (July 13, 2026, 4 p.m. EDT)
After hours: 4.24 +0.09 (2.070%) ⇧ (July 13, 2026, 7:55 p.m. EDT)

Short-term:★☆☆☆☆Long-term:⯪☆☆☆☆Dividends:☆☆☆☆☆
Hot Take | July 11, 2026, 3:14 a.m. EDT

The immediate outlook is severely clouded by a massive 14.5% drop in the last two weeks, leaving the stock trading far below its 50-day average. While analysts have set a lofty $25.50 target, this is disconnected from the brutal reality of the business: the company has suffered four consecutive years of negative annual returns, with the most recent year seeing a nearly 99% collapse in value. This multi-year decline signals a fundamental structural deterioration rather than a temporary setback. Compounding the distress, the company is burning through cash with significant negative free cash flow and no dividend to provide any cushion. The recent news of a reverse split approval and stock tumbling despite positive trial data suggests the market is aggressively repricing the asset for survival, not growth.

Model Selection — Backtest MAE (log-scale, lower is better)
ModelMAE
AutoTheta ✓0.320869
AutoARIMA0.329492
AutoETS0.329803
MSTL0.340960
MSTL_840.538858
MSTL_1150.572912
MSTL_84_1150.768132

Forecast horizon: 60 days | Selected: AutoTheta

Forecast Reliability
Score 28%
H-stat 12.34
Ljung-Box p 0.000
Jarque-Bera p 0.068
Excess Kurtosis -1.44
Attribute Value
Sector Healthcare
Debt to Equity Ratio 38.081
Market Cap 5,171,336
Trailing P/E 0.00
Forward P/E -0.19
Beta 1.67
Website https://aptevotherapeutics.com

Info Dump

Attribute Value
52 Week Change -0.9258004
Address1 2,401 4th Avenue
Address2 Suite 1050
All Time High 68,020,448.0
All Time Low 3.68
Ask 5.06
Ask Size 2
Average Daily Volume10 Day 160,840
Average Daily Volume3 Month 54,850
Average Volume 54,850
Average Volume10Days 160,840
Beta 1.671
Bid 3.06
Bid Size 2
Book Value 9.646
City Seattle
Compensation As Of Epoch Date 1,767,139,200
Country United States
Crypto Tradeable 0
Currency USD
Current Price 4.15
Current Ratio 3.358
Custom Price Alert Confidence HIGH
Date Short Interest 1,782,777,600
Day High 4.29
Day Low 3.875
Debt To Equity 38.081
Display Name Aptevo Therapeutics
Dividend Date 1,585,267,200
Earnings Timestamp End 1,754,915,400
Earnings Timestamp Start 1,754,483,400
Ebitda -26,455,000
Ebitda Margins 0.0
Enterprise To Ebitda 0.186
Enterprise Value -4,931,664
Eps Current Year -24.13
Eps Forward -21.46
Eps Trailing Twelve Months 1,488.13
Esg Populated 0
Exchange NCM
Exchange Data Delayed By 0
Exchange Timezone Name America/New_York
Exchange Timezone Short Name EDT
Fax 206 838 0503
Fifty Day Average 4.755
Fifty Day Average Change -0.605
Fifty Day Average Change Percent -0.12723449
Fifty Two Week Change Percent -92.58004
Fifty Two Week High 59.4
Fifty Two Week High Change -55.25
Fifty Two Week High Change Percent -0.93013465
Fifty Two Week Low 3.68
Fifty Two Week Low Change 0.47000003
Fifty Two Week Low Change Percent 0.12771739
Fifty Two Week Range 3.68 - 59.4
Financial Currency USD
First Trade Date Milliseconds 1,469,021,400,000
Float Shares 1,093,632
Forward Eps -21.46
Forward P E -0.19338305
Free Cashflow -17,197,124
Full Exchange Name NasdaqCM
Full Time Employees 33
Gmt Off Set Milliseconds -14,400,000
Gross Margins 0.0
Has Pre Post Market Data 1
Held Percent Insiders 0.07967
Held Percent Institutions 0.044549998
Implied Shares Outstanding 1,246,105
Industry Biotechnology
Industry Disp Biotechnology
Industry Key biotechnology
Is Earnings Date Estimate 1
Language en-US
Last Fiscal Year End 1,767,139,200
Last Split Date 1,767,052,800
Last Split Factor 1:18
Long Business Summary Aptevo Therapeutics Inc., a clinical-stage research and development biotechnology company, focuses on developing immunotherapeutic candidates for the treatment of various forms of cancer in the United States. The company develops its products using ADAPTIR and ADAPTIR-FLEX platforms to generate monospecific, bispecific, and multi-specific antibody candidates capable of enhancing the human immune system against cancer cells. Its lead clinical blood cancer candidate is mipletamig that is in Phase 1b/2 clinical trial for the treatment of acute myelogenous leukemia. The company also develops ALG.APV-527, a novel investigational bispecific ADAPTIR candidate that is in Phase 1 clinical trial for the treatment malignant pleural mesothelioma, non-small cell lung, gastric/gastro-esophageal, head and neck squamous cell carcinoma, pancreatic, renal, ovarian, prostate, breast, cervical, colorectal, endometrial, and bladder cancers; APVO603, a preclinical dual agonist bispecific ADAPTIR candidate to treat multiple solid tumors; APVO442, a preclinical bispecific candidate based on the ADAPTIR-FLEX platform technology for the treatment of multiple solid tumors; and APVO711, a preclinical dual mechanism bispecific ADAPTIR candidate to treat prostate cancer. It has a collaboration and option agreement with Alligator Bioscience AB to develop ALG.APV-527. Aptevo Therapeutics Inc. was incorporated in 2016 and is headquartered in Seattle, Washington.
Long Name Aptevo Therapeutics Inc.
Market us_market
Market Cap 5,171,336
Market State PREPRE
Max Age 86,400
Message Board Id finmb_331280020
Most Recent Quarter 1,774,915,200
Net Income To Common -26,353,000
Next Fiscal Year End 1,798,675,200
Non Diluted Market Cap 4,909,653
Number Of Analyst Opinions 2
Open 3.96
Operating Cashflow -26,982,000
Operating Margins 0.0
Payout Ratio 0.0
Phone 206 838 0500
Post Market Change 0.08589983
Post Market Change Percent 2.0698755
Post Market Price 4.2359
Post Market Time 1,783,986,902
Previous Close 3.94
Price Eps Current Year -0.17198509
Price Hint 4
Price To Book 0.43023017
Profit Margins 0.0
Quick Ratio 3.051
Quote Source Name Nasdaq Real Time Price
Quote Type EQUITY
Recommendation Key none
Region US
Regular Market Change 0.21
Regular Market Change Percent 5.32995
Regular Market Day High 4.29
Regular Market Day Low 3.875
Regular Market Day Range 3.875 - 4.29
Regular Market Open 3.96
Regular Market Previous Close 3.94
Regular Market Price 4.15
Regular Market Time 1,783,972,801
Regular Market Volume 80,549
Return On Assets -1.18029
Return On Equity -5.17921
Sand P52 Week Change 0.20847368
Sector Healthcare
Sector Disp Healthcare
Sector Key healthcare
Shares Outstanding 1,246,105
Shares Percent Shares Out 0.0637
Shares Short 79,436
Shares Short Previous Month Date 1,780,012,800
Shares Short Prior Month 80,160
Short Name Aptevo Therapeutics Inc.
Short Percent Of Float 0.0638
Short Ratio 2.55
Source Interval 15
State WA
Symbol APVO
Target High Price 30.0
Target Low Price 21.0
Target Mean Price 25.5
Target Median Price 25.5
Total Cash 14,525,000
Total Cash Per Share 11.656
Total Debt 4,422,000
Tradeable 0
Trailing Annual Dividend Rate 0.0
Trailing Annual Dividend Yield 0.0
Trailing Eps 1,488.13
Trailing P E 0.0027887349
Trailing Peg Ratio None
Triggerable 1
Two Hundred Day Average 12.18713
Two Hundred Day Average Change -8.03713
Two Hundred Day Average Change Percent -0.6594769
Type Disp Equity
Volume 80,549
Website https://aptevotherapeutics.com
Zip 98,121