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Aprea Therapeutics, Inc. (APRE)

Healthcare | Biotechnology | Doylestown, United States | NasdaqCM
0.84 USD -0.02 (-2.500%) ⇩ (Aug. 28, 2026, 4 p.m. EDT)
After hours: 0.86 +0.02 (2.826%) ⇧ (Aug. 28, 2026, 7:52 p.m. EDT)

Short-term:★★⯪☆☆Long-term:⯪☆☆☆☆Dividends:☆☆☆☆☆
Hot Take | Aug. 22, 2026, 5:27 a.m. EDT

The immediate outlook is neutral-to-slightly-bearish despite a recent bounce, as the stock trades at a significant discount to its moving averages and faces a critical regulatory deadline highlighted by recent news regarding an 180-day extension to meet a $1 bid. The recent price action shows a modest recovery from lows, but the underlying momentum remains fragile given the heavy volume and the fact that the price is still well below the 50-day average. Looking further ahead, the investment case is severely compromised by a catastrophic multi-year decline; the asset has lost nearly 99.7% of its value over the last five years, with every single year showing negative returns. This relentless downward trajectory suggests a fundamental business failure or a value trap where the market has permanently repriced the asset, rendering any current fundamentals irrelevant. Finally, there is no income component to consider, as the company has not paid a dividend in the last five years, offering no cushion for investors in this high-risk biotech sector.

Model Selection — Backtest MAE (log-scale, lower is better)
ModelMAE
AutoARIMA ✓0.218828
MSTL0.223753
AutoETS0.227289
AutoTheta0.294495

Forecast horizon: 45 days | Selected: AutoARIMA

Forecast Reliability
Score 34%
H-stat 3.38
Ljung-Box p 0.000
Jarque-Bera p 0.210
Excess Kurtosis -0.89
Attribute Value
Sector Healthcare
Market Cap 10,558,926
Forward P/E -2.89
Beta 1.59
Website https://aprea.com

Info Dump

Attribute Value
52 Week Change -0.45222932
Address1 3,805 Old Easton Road
All Time High 1,062.2
All Time Low 0.474
Ask 0.8594
Ask Size 2
Audit Risk 9
Average Analyst Rating 1.3 - Strong Buy
Average Daily Volume10 Day 913,470
Average Daily Volume3 Month 215,061
Average Volume 215,061
Average Volume10Days 913,470
Beta 1.588
Bid 0.7937
Bid Size 1
Board Risk 7
Book Value 3.105
City Doylestown
Compensation As Of Epoch Date 1,767,139,200
Compensation Risk 8
Country United States
Crypto Tradeable 0
Currency USD
Current Price 0.8386
Current Ratio 13.554
Custom Price Alert Confidence HIGH
Date Short Interest 1,786,665,600
Day High 0.9099
Day Low 0.8202
Display Name Aprea Therapeutics
Earnings Timestamp End 1,755,261,000
Earnings Timestamp Start 1,754,915,400
Ebitda -13,201,041
Ebitda Margins 0.0
Enterprise To Ebitda 2.269
Enterprise To Revenue -5,775.726
Enterprise Value -29,947,140
Eps Current Year -0.31333
Eps Forward -0.29
Eps Trailing Twelve Months -0.94
Esg Populated 0
Exchange NCM
Exchange Data Delayed By 0
Exchange Timezone Name America/New_York
Exchange Timezone Short Name EDT
Fifty Day Average 0.71202
Fifty Day Average Change 0.12658
Fifty Day Average Change Percent 0.1777759
Fifty Two Week Change Percent -45.22293
Fifty Two Week High 1.69
Fifty Two Week High Change -0.8514001
Fifty Two Week High Change Percent -0.50378704
Fifty Two Week Low 0.548
Fifty Two Week Low Change 0.2906
Fifty Two Week Low Change Percent 0.530292
Fifty Two Week Range 0.548 - 1.69
Financial Currency USD
First Trade Date Milliseconds 1,570,109,400,000
Float Shares 7,910,129
Forward Eps -0.29
Forward P E -2.891724
Free Cashflow -8,151,741
Full Exchange Name NasdaqCM
Full Time Employees 8
Fullday Change -0.0215
Fullday Change Percent -2.49971
Fullday Price 0.8623
Gmt Off Set Milliseconds -14,400,000
Governance Epoch Date 1,785,542,400
Gross Margins 0.0
Gross Profits -6,715,780
Has Pre Post Market Data 1
Held Percent Insiders 0.09174
Held Percent Institutions 0.18832001
Implied Shares Outstanding 12,591,136
Industry Biotechnology
Industry Disp Biotechnology
Industry Key biotechnology
Is Earnings Date Estimate 1
Language en-US
Last Fiscal Year End 1,767,139,200
Last Split Date 1,676,246,400
Last Split Factor 1:20
Long Business Summary Aprea Therapeutics, Inc., a clinical-stage biopharmaceutical company, focuses on developing and commercializing novel synthetic lethality-based cancer therapeutics that targets DNA damage response pathways. Its lead product candidates are APR-1051, an orally bioavailable small-molecule inhibitor of WEE1 kinase that is in Phase 1 clinical trial for the treatment of patients with advanced solid tumors with biomarkers and ATRN-119, an ATR inhibitor, which is in Phase 1/2a clinical trial for solid tumor indications. The company is headquartered in Doylestown, Pennsylvania.
Long Name Aprea Therapeutics, Inc.
Market us_market
Market Cap 10,558,926
Market State CLOSED
Max Age 86,400
Message Board Id finmb_329831339
Most Recent Quarter 1,782,777,600
Net Income To Common -12,307,261
Next Fiscal Year End 1,798,675,200
Non Diluted Market Cap 10,829,636
Number Of Analyst Opinions 4
Open 0.88
Operating Cashflow -12,168,011
Operating Margins -2,550.2551
Overall Risk 8
Payout Ratio 0.0
Phone 215 948 4119
Post Market Change 0.023699999
Post Market Change Percent 2.8261387
Post Market Price 0.8623
Post Market Time 1,787,961,174
Previous Close 0.8601
Price Eps Current Year -2.6764114
Price Hint 4
Price To Book 0.2700805
Price To Sales Trailing12 Months 2,036.437
Profit Margins 0.0
Quick Ratio 13.334
Quote Source Name Nasdaq Real Time Price
Quote Type EQUITY
Recommendation Key strong_buy
Recommendation Mean 1.25
Region US
Regular Market Change -0.021499991
Regular Market Change Percent -2.4997084
Regular Market Day High 0.9099
Regular Market Day Low 0.8202
Regular Market Day Range 0.8202 - 0.9099
Regular Market Open 0.88
Regular Market Previous Close 0.8601
Regular Market Price 0.8386
Regular Market Time 1,787,947,200
Regular Market Volume 343,096
Return On Assets -0.27733
Return On Equity -0.46147
Revenue Per Share 0.0
Sand P52 Week Change 0.20504117
Sector Healthcare
Sector Disp Healthcare
Sector Key healthcare
Share Holder Rights Risk 8
Shares Outstanding 12,591,136
Shares Percent Shares Out 0.0004
Shares Short 5,487
Shares Short Previous Month Date 1,784,073,600
Shares Short Prior Month 60,595
Short Name Aprea Therapeutics, Inc.
Short Percent Of Float 0.0005
Short Ratio 0.11
Source Interval 15
State PA
Symbol APRE
Target High Price 5.0
Target Low Price 1.2
Target Mean Price 3.55
Target Median Price 4.0
Total Cash 41,233,428
Total Cash Per Share 3.275
Total Debt 0
Total Revenue 5,185
Tradeable 0
Trailing Annual Dividend Rate 0.0
Trailing Annual Dividend Yield 0.0
Trailing Eps -0.94
Trailing Peg Ratio None
Triggerable 1
Two Hundred Day Average 0.83138
Two Hundred Day Average Change 0.00721997
Two Hundred Day Average Change Percent 0.00868432
Type Disp Equity
Volume 343,096
Website https://aprea.com
Zip 18,902