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Apogee Therapeutics, Inc. (APGE)

Healthcare | Biotechnology | Waltham, United States | NasdaqGM
133.82 USD +0.17 (0.127%) ⇧ (July 13, 2026, 4 p.m. EDT)
After hours: 133.82

Short-term:★★★★⯪Long-term:★★★☆☆Dividends:☆☆☆☆☆
Hot Take | July 11, 2026, 4:53 a.m. EDT

The acquisition announcement by AbbVie has transformed this stock into a high-conviction takeover play, pushing the price to fresh highs and validating the short-term bullish thesis. However, the underlying business remains cash-burning with negative earnings, meaning the valuation is entirely dependent on the deal closing rather than organic growth. While the price momentum is robust, the options market is screaming caution with put premiums far exceeding call interest, hinting at a potential sharp pullback once the deal details settle. Investors should view this as a high-risk, high-reward event-driven trade rather than a traditional equity investment.

Model Selection — Backtest MAE (log-scale, lower is better)
ModelMAE
MSTL ✓0.103242
AutoARIMA0.108057
AutoETS0.108058
AutoTheta0.116394

Forecast horizon: 45 days | Selected: MSTL

Forecast Reliability
Score 23%
H-stat 7.42
Ljung-Box p 0.000
Jarque-Bera p 0.000
Excess Kurtosis 4.92
Attribute Value
Sector Healthcare
Debt to Equity Ratio 0.641
Market Cap 10,061,084,672
Forward P/E -25.79
Beta 0.33
Website https://www.apogeetherapeutics.com

As of July 11, 2026, 4:53 a.m. EDT: Market participants are aggressively purchasing downside protection, evidenced by implied volatility on put options being nearly nine times higher than on calls. Open interest is heavily skewed toward out-of-the-money puts, indicating a significant hedge against a potential price collapse despite the acquisition headlines. Call activity remains thin with low premiums, suggesting limited speculative upside demand compared to the defensive positioning.


Info Dump

Attribute Value
52 Week Change 2.4375
Address1 Building 17
Address2 Suite 102b 221 Crescent Street
All Time High 133.87
All Time Low 14.19
Ask 171.17
Ask Size 2
Audit Risk 7
Average Daily Volume10 Day 2,867,610
Average Daily Volume3 Month 2,550,898
Average Volume 2,550,898
Average Volume10Days 2,867,610
Beta 0.325
Bid 96.12
Bid Size 2
Board Risk 5
Book Value 16.87
City Waltham
Compensation As Of Epoch Date 1,767,139,200
Compensation Risk 8
Country United States
Crypto Tradeable 0
Currency USD
Current Price 133.82
Current Ratio 32.587
Custom Price Alert Confidence HIGH
Date Short Interest 1,782,777,600
Day High 133.88
Day Low 133.55
Debt To Equity 0.641
Display Name Apogee Therapeutics
Earnings Timestamp 1,778,502,600
Earnings Timestamp End 1,786,365,000
Earnings Timestamp Start 1,786,365,000
Ebitda -303,652,000
Ebitda Margins 0.0
Enterprise To Ebitda -29.566
Enterprise Value 8,977,709,056
Eps Current Year -4.41291
Eps Forward -5.18847
Eps Trailing Twelve Months -4.33
Esg Populated 0
Exchange NGM
Exchange Data Delayed By 0
Exchange Timezone Name America/New_York
Exchange Timezone Short Name EDT
Fifty Day Average 97.2326
Fifty Day Average Change 36.58741
Fifty Day Average Change Percent 0.3762875
Fifty Two Week Change Percent 243.75
Fifty Two Week High 133.88
Fifty Two Week High Change -0.05999756
Fifty Two Week High Change Percent -0.00044814427
Fifty Two Week Low 34.34
Fifty Two Week Low Change 99.48001
Fifty Two Week Low Change Percent 2.8969135
Fifty Two Week Range 34.34 - 133.88
Financial Currency USD
First Trade Date Milliseconds 1,689,341,400,000
Float Shares 57,998,545
Forward Eps -5.18847
Forward P E -25.791805
Free Cashflow -142,579,376
Full Exchange Name NasdaqGM
Full Time Employees 261
Gmt Off Set Milliseconds -14,400,000
Governance Epoch Date 1,782,864,000
Gross Margins 0.0
Has Pre Post Market Data 1
Held Percent Insiders 0.05959
Held Percent Institutions 1.1032901
Implied Shares Outstanding 75,183,715
Industry Biotechnology
Industry Disp Biotechnology
Industry Key biotechnology
Ipo Expected Date 2,023-07-14
Is Earnings Date Estimate 1
Language en-US
Last Fiscal Year End 1,767,139,200
Long Business Summary Apogee Therapeutics, Inc., a clinical stage biotechnology company, develops novel biologics for the treatment of atopic dermatitis, asthma, eosinophilic esophagitis, chronic obstructive pulmonary disease, and other inflammatory and immunology indications in the United States. The company develops Zumilokibart (APG777), a subcutaneous (SQ) extended half-life monoclonal antibody (mAb) for the treatment of atopic dermatitis, which is in phase 2 clinical trials; and for the treatment of asthma and eosinophilic esophagitis which is in phase 1 clinical trial. It also develops APG279 which is in phase 1 clinical trial for the treatment of atopic dermatitis; APG273 which is in phase 1 clinical trial for the treatment of asthma and chronic obstructive pulmonary disease; and APG808, an SQ extended half-life mAb targeting IL-4Ra for the treatment of Type 2 allergic diseases. Apogee Therapeutics, Inc. was incorporated in 2022 and is headquartered in Waltham, Massachusetts.
Long Name Apogee Therapeutics, Inc.
Market us_market
Market Cap 10,061,084,672
Market State PREPRE
Max Age 86,400
Message Board Id finmb_1816591253
Most Recent Quarter 1,774,915,200
Net Income To Common -274,615,008
Next Fiscal Year End 1,798,675,200
Non Diluted Market Cap 10,047,927,591
Number Of Analyst Opinions 12
Open 133.55
Operating Cashflow -234,543,008
Operating Margins 0.0
Overall Risk 9
Payout Ratio 0.0
Phone 650 394 5230
Post Market Change 0.0
Post Market Change Percent 0.0
Post Market Price 133.82
Post Market Time 1,783,981,118
Previous Close 133.65
Price Eps Current Year -30.324663
Price Hint 2
Price To Book 7.9324245
Profit Margins 0.0
Quick Ratio 32.385
Quote Source Name Nasdaq Real Time Price
Quote Type EQUITY
Recommendation Key none
Region US
Regular Market Change 0.170013
Regular Market Change Percent 0.127208
Regular Market Day High 133.88
Regular Market Day Low 133.55
Regular Market Day Range 133.55 - 133.88
Regular Market Open 133.55
Regular Market Previous Close 133.65
Regular Market Price 133.82
Regular Market Time 1,783,972,801
Regular Market Volume 800,350
Return On Assets -0.19004999
Return On Equity -0.2847
Sand P52 Week Change 0.20847368
Sector Healthcare
Sector Disp Healthcare
Sector Key healthcare
Share Holder Rights Risk 10
Shares Outstanding 61,697,073
Shares Percent Shares Out 0.0687
Shares Short 5,161,455
Shares Short Previous Month Date 1,780,012,800
Shares Short Prior Month 10,526,394
Short Name Apogee Therapeutics, Inc.
Short Percent Of Float 0.1084
Short Ratio 0.94
Source Interval 15
State MA
Symbol APGE
Target High Price 137.0
Target Low Price 81.0
Target Mean Price 130.5275
Target Median Price 135.0
Total Cash 1,059,884,992
Total Cash Per Share 14.142
Total Debt 8,047,000
Tradeable 0
Trailing Annual Dividend Rate 0.0
Trailing Annual Dividend Yield 0.0
Trailing Eps -4.33
Trailing Peg Ratio None
Triggerable 1
Two Hundred Day Average 76.0591
Two Hundred Day Average Change 57.76091
Two Hundred Day Average Change Percent 0.75942147
Type Disp Equity
Volume 800,350
Website https://www.apogeetherapeutics.com
Zip 2,453