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Alto Neuroscience, Inc. (ANRO)

Healthcare | Biotechnology | Mountain View, United States | NYSE
27.55 USD +1.49 (5.717%) ⇧ (April 17, 2026, 2:28 p.m. EDT)

Short-term: ★★☆☆☆ | Long-term: ★☆☆☆☆ | Dividends: ☆☆☆☆☆
Hot Take | April 11, 2026, 2:53 p.m. EDT

ANRO is a highly volatile stock with a significant short interest and negative fundamentals, making it a risky short-term play. The recent news includes mixed analyst opinions, with some recommending a buy while others are pessimistic. The current price is near the 52-week high, but the stock has a history of significant price swings. While there are some positive analyst ratings, the overall fundamentals and high volatility make it a speculative investment. Long-term investors should be cautious, as the stock lacks consistent dividends and has a negative earnings outlook. Short-term traders might consider the stock for momentum or options strategies, but the high risk should be weighed against potential rewards.

Model Selection — Backtest MAE (log-scale, lower is better)
ModelMAE
MSTL ✓0.202188
AutoARIMA0.204357
AutoETS0.204358
AutoTheta0.229625

Forecast horizon: 45 days | Selected: MSTL

Forecast Reliability
Score 44%
H-stat 10.02
Ljung-Box p 0.000
Jarque-Bera p 0.378
Excess Kurtosis -0.54
Attribute Value
Sector Healthcare
Debt to Equity Ratio 15.851
Market Cap 965,699,264
Forward P/E -12.11
Beta 2.06
Website https://www.altoneuroscience.com

As of April 11, 2026, 2:53 p.m. EDT: Options speculators are showing mixed signals. The calls show a concentration of open interest (OI) around the 22.5 strike, which is near the current price, suggesting some bullish sentiment. However, the puts also show significant OI around the 22.5 strike, indicating potential bearishness. The high IV (implied volatility) on puts, especially on the 2026-10-16 expiration, suggests increased uncertainty or fear, which could lead to a volatile price movement. The overall options activity indicates a cautious outlook with potential for both upward and downward moves.


Info Dump

Attribute Value
52 Week Change 10.2327585
Address1 650 Castro Street
Address2 Suite 450
All Time High 27.5
All Time Low 1.6
Ask 27.52
Ask Size 100
Average Analyst Rating 1.2 - Strong Buy
Average Daily Volume10 Day 394,870
Average Daily Volume3 Month 280,429
Average Volume 280,429
Average Volume10Days 394,870
Beta 2.059
Bid 27.35
Bid Size 100
Book Value 4.735
City Mountain View
Compensation As Of Epoch Date 1,767,139,200
Country United States
Crypto Tradeable 0
Currency USD
Current Price 27.5499
Current Ratio 15.693
Custom Price Alert Confidence HIGH
Date Short Interest 1,774,915,200
Day High 28.11
Day Low 25.805
Debt To Equity 15.851
Display Name Alto Neuroscience
Earnings Timestamp 1,773,664,200
Earnings Timestamp End 1,778,761,800
Earnings Timestamp Start 1,778,761,800
Ebitda -65,703,000
Ebitda Margins 0.0
Enterprise To Ebitda -10.349
Enterprise Value 679,974,144
Eps Current Year -2.1
Eps Forward -2.275
Eps Trailing Twelve Months -2.19
Esg Populated 0
Exchange NYQ
Exchange Data Delayed By 0
Exchange Timezone Name America/New_York
Exchange Timezone Short Name EDT
Fifty Day Average 20.5634
Fifty Day Average Change 6.9865
Fifty Day Average Change Percent 0.3397541
Fifty Two Week Change Percent 1,023.2759
Fifty Two Week High 28.11
Fifty Two Week High Change -0.56010056
Fifty Two Week High Change Percent -0.019925313
Fifty Two Week Low 2.12
Fifty Two Week Low Change 25.429901
Fifty Two Week Low Change Percent 11.995237
Fifty Two Week Range 2.12 - 28.11
Financial Currency USD
First Trade Date Milliseconds 1,706,884,200,000
Float Shares 19,191,588
Forward Eps -2.275
Forward P E -12.109846
Free Cashflow -33,950,624
Full Exchange Name NYSE
Full Time Employees 68
Gmt Off Set Milliseconds -14,400,000
Gross Margins 0.0
Has Pre Post Market Data 1
Held Percent Insiders 0.062529996
Held Percent Institutions 0.7704
Implied Shares Outstanding 35,052,731
Industry Biotechnology
Industry Disp Biotechnology
Industry Key biotechnology
Is Earnings Date Estimate 1
Language en-US
Last Fiscal Year End 1,767,139,200
Long Business Summary Alto Neuroscience, Inc. operates as a clinical-stage biopharmaceutical company in the United States. The company's product pipeline includes ALTO-100, which is in Phase 2b clinical trial for the treatment of patients with bipolar depression (BPD). It also develops ALTO-300, a small molecule melatonergic agonist and serotonergic antagonist with antidepressant properties, which is in Phase 2b clinical trial to treat patients with major depressive disorder (MDD); ALTO-101, a novel small molecule phosphodiesterase 4 inhibitor that is in Phase 2 proof-of-concept (POC) trial for the treatment of cognitive impairment associated with schizophrenia; ALTO-203, a novel small-molecule histamine H3 receptor inverse agonist, which is in Phase 2 POC trial to treat patients with MDD and higher levels of anhedonia; ALTO-202, an investigational orally bioavailable antagonist of the GluN2B subunit of the NMDA receptor that is in Phase 1 clinical trial for the treatment of MDD; and ALTO-208, a fixed-dose combination of pramipexole and aprepitant, an antiemetic, neurokinin-1 (NK-1) receptor antagonist for patients with Parkinson's disease for patients with Parkinson's disease. The company was incorporated in 2019 and is headquartered in Mountain View, California.
Market us_market
Market Cap 965,699,264
Market State REGULAR
Max Age 86,400
Message Board Id finmb_1675972978
Most Recent Quarter 1,767,139,200
Net Income To Common -63,238,000
Next Fiscal Year End 1,798,675,200
Non Diluted Market Cap 913,474,169
Number Of Analyst Opinions 9
Open 26.25
Operating Cashflow -51,769,000
Operating Margins 0.0
Payout Ratio 0.0
Phone 650 200 0412
Previous Close 26.06
Price Eps Current Year -13.119
Price Hint 2
Price To Book 5.8183527
Profit Margins 0.0
Quick Ratio 15.584
Quote Source Name Nasdaq Real Time Price
Quote Type EQUITY
Recommendation Key strong_buy
Recommendation Mean 1.2
Region US
Regular Market Change 1.4899006
Regular Market Change Percent 5.717193
Regular Market Day High 28.11
Regular Market Day Low 25.805
Regular Market Day Range 25.805 - 28.11
Regular Market Open 26.25
Regular Market Previous Close 26.06
Regular Market Price 27.5499
Regular Market Time 1,776,450,482
Regular Market Volume 180,447
Return On Assets -0.22900999
Return On Equity -0.41796002
Sand P52 Week Change 0.36506534
Sector Healthcare
Sector Disp Healthcare
Sector Key healthcare
Shares Outstanding 35,052,731
Shares Percent Shares Out 0.0642
Shares Short 2,051,993
Shares Short Previous Month Date 1,772,150,400
Shares Short Prior Month 2,043,099
Short Name Alto Neuroscience, Inc.
Short Percent Of Float 0.0783
Short Ratio 6.52
Source Interval 15
State CA
Symbol ANRO
Target High Price 50.0
Target Low Price 21.0
Target Mean Price 35.24444
Target Median Price 35.0
Total Cash 176,484,000
Total Cash Per Share 5.525
Total Debt 23,958,000
Tradeable 0
Trailing Annual Dividend Rate 0.0
Trailing Annual Dividend Yield 0.0
Trailing Eps -2.19
Trailing Peg Ratio None
Triggerable 1
Two Hundred Day Average 12.03835
Two Hundred Day Average Change 15.51155
Two Hundred Day Average Change Percent 1.2885113
Type Disp Equity
Volume 180,447
Website https://www.altoneuroscience.com
Zip 94,041