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AnaptysBio, Inc. (ANAB)

Healthcare | Biotechnology | San Diego, United States | NasdaqGS
67.51 USD +0.61 (0.912%) ⇧ (April 17, 2026, 4 p.m. EDT)
After hours: 67.53 +0.02 (0.030%) ⇧ (April 17, 2026, 7:32 p.m. EDT)

Short-term: ★★★☆☆ | Long-term: ★★☆☆☆ | Dividends: ☆☆☆☆☆
Hot Take | April 11, 2026, 4:13 p.m. EDT

ANAB is showing signs of potential short-term momentum with recent price increases and analyst recommendations leaning towards a 'Moderate Buy'. However, the company's fundamentals are weak with negative profit margins and high debt-to-equity ratio. The lack of dividends and the high overall risk make it less attractive for long-term investors. While the options market suggests some bullish sentiment, the overall risk profile and weak fundamentals indicate caution. Investors should monitor earnings reports and any further news for potential shifts in sentiment.

Model Selection — Backtest MAE (log-scale, lower is better)
ModelMAE
AutoTheta ✓0.097103
MSTL0.181059
AutoETS0.198581
AutoARIMA0.200311

Forecast horizon: 45 days | Selected: AutoTheta

Forecast Reliability
Score 45%
H-stat 7.47
Ljung-Box p 0.000
Jarque-Bera p 0.236
Excess Kurtosis -1.19
Attribute Value
Sector Healthcare
Debt to Equity Ratio 781.08
Revenue per Share 8.158
Market Cap 1,940,794,880
Forward P/E -19.08
Beta 0.41
Profit Margins -5.64%
Website https://www.anaptysbio.com

As of April 11, 2026, 4:13 p.m. EDT: Options activity indicates mixed signals. Call options show some bullish positioning with higher open interest and volume around the current price, suggesting potential for upward movement. However, put options show limited activity, with most focus on out-of-the-money strikes, which may indicate limited bearish sentiment. The low implied volatility and limited open interest in puts suggest that traders are not heavily betting on a significant drop. Overall, the options market seems to be cautiously optimistic with a slight tilt towards bullish sentiment.


Info Dump

Attribute Value
52 Week Change 2.244423
Address1 10,770 Wateridge Circle
Address2 Suite 210
All Time High 134.0
All Time Low 10.0
Ask 84.3
Ask Size 2
Audit Risk 5
Average Daily Volume10 Day 536,530
Average Daily Volume3 Month 540,081
Average Volume 540,081
Average Volume10Days 536,530
Beta 0.406
Bid 48.52
Bid Size 2
Board Risk 7
Book Value 1.328
City San Diego
Compensation As Of Epoch Date 1,735,603,200
Compensation Risk 10
Country United States
Crypto Tradeable 0
Currency USD
Current Price 67.51
Current Ratio 9.068
Custom Price Alert Confidence HIGH
Date Short Interest 1,774,915,200
Day High 68.73
Day Low 65.69
Debt To Equity 781.08
Display Name AnaptysBio
Earnings Timestamp 1,772,571,600
Earnings Timestamp End 1,778,011,200
Earnings Timestamp Start 1,778,011,200
Ebitda 48,455,000
Ebitda Margins 0.20653999
Enterprise To Ebitda 39.62
Enterprise To Revenue 8.183
Enterprise Value 1,919,796,736
Eps Current Year -4.07633
Eps Forward -3.53757
Eps Trailing Twelve Months -0.46
Esg Populated 0
Exchange NMS
Exchange Data Delayed By 0
Exchange Timezone Name America/New_York
Exchange Timezone Short Name EDT
Fifty Day Average 59.2934
Fifty Day Average Change 8.216602
Fifty Day Average Change Percent 0.13857533
Fifty Two Week Change Percent 224.44229
Fifty Two Week High 73.3
Fifty Two Week High Change -5.790001
Fifty Two Week High Change Percent -0.07899046
Fifty Two Week Low 17.106
Fifty Two Week Low Change 50.404
Fifty Two Week Low Change Percent 2.9465683
Fifty Two Week Range 17.106 - 73.3
Financial Currency USD
First Trade Date Milliseconds 1,485,441,000,000
Float Shares 17,263,040
Forward Eps -3.53757
Forward P E -19.083721
Free Cashflow 19,342,876
Full Exchange Name NasdaqGS
Full Time Employees 104
Gmt Off Set Milliseconds -14,400,000
Governance Epoch Date 1,775,001,600
Gross Margins 0.42043
Gross Profits 98,633,000
Has Pre Post Market Data 1
Held Percent Insiders 0.05864
Held Percent Institutions 1.01136
Implied Shares Outstanding 28,748,255
Industry Biotechnology
Industry Disp Biotechnology
Industry Key biotechnology
Is Earnings Date Estimate 1
Language en-US
Last Fiscal Year End 1,767,139,200
Long Business Summary AnaptysBio, Inc., a clinical-stage biotechnology company, focuses in delivering immunology therapeutics for autoimmune and inflammatory diseases in the United States. The company's products include Rosnilimab, a selective pathogenic T cell deplete which completed a Phase 2b trial for the treatment of moderate-to-severe rheumatoid arthritis; ANB033, a CD122 antagonist, which is in a Phase 1b trial for celiac disease and eosinophilic esophagitis; ANB101, a BDCA2 modulator antibody which is in Phase 1a trial that specifically targets plasmacytoid dendritic cells and inhibits interferon secretion and modulates antigen presentation; dostarlimab, a PD-1 antagonist for various solid tumor indications; and Imsidolimab, an antibody that inhibits the interleukin-36 receptor, which is in the Phase 3 development for the treatment of generalized pustular psoriasis. It focuses on developing various antibody programs that are advanced to preclinical and clinical milestones under its collaborations. It has collaborations agreement with GSK and Vanda. The company was formerly known as Anaptys Biosciences, Inc. and changed its name to AnaptysBio, Inc. in July 2006. AnaptysBio, Inc. was incorporated in 2005 and is based in San Diego, California.
Long Name AnaptysBio, Inc.
Market us_market
Market Cap 1,940,794,880
Market State CLOSED
Max Age 86,400
Message Board Id finmb_28462113
Most Recent Quarter 1,767,139,200
Net Income To Common -13,232,000
Next Fiscal Year End 1,798,675,200
Non Diluted Market Cap 1,940,650,953
Number Of Analyst Opinions 11
Open 68.34
Operating Cashflow 19,697,000
Operating Margins 0.61803
Overall Risk 9
Payout Ratio 0.0
Phone 858 362 6295
Post Market Change 0.019996643
Post Market Change Percent 0.029620267
Post Market Price 67.53
Post Market Time 1,776,468,723
Previous Close 66.9
Price Eps Current Year -16.561466
Price Hint 2
Price To Book 50.835846
Price To Sales Trailing12 Months 8.272676
Profit Margins -0.056399997
Quick Ratio 8.945
Quote Source Name Nasdaq Real Time Price
Quote Type EQUITY
Recommendation Key none
Region US
Regular Market Change 0.610001
Regular Market Change Percent 0.91181
Regular Market Day High 68.73
Regular Market Day Low 65.69
Regular Market Day Range 65.69 - 68.73
Regular Market Open 68.34
Regular Market Previous Close 66.9
Regular Market Price 67.51
Regular Market Time 1,776,456,001
Regular Market Volume 621,101
Return On Assets 0.07058
Return On Equity -0.24486
Revenue Growth 1.511
Revenue Per Share 8.158
Sand P52 Week Change 0.36506534
Sector Healthcare
Sector Disp Healthcare
Sector Key healthcare
Share Holder Rights Risk 8
Shares Outstanding 28,748,255
Shares Percent Shares Out 0.1674
Shares Short 4,811,520
Shares Short Previous Month Date 1,772,150,400
Shares Short Prior Month 5,366,443
Short Name AnaptysBio, Inc.
Short Percent Of Float 0.3075
Short Ratio 7.13
Source Interval 15
State CA
Symbol ANAB
Target High Price 140.0
Target Low Price 50.0
Target Mean Price 79.90909
Target Median Price 75.0
Total Cash 311,638,016
Total Cash Per Share 10.84
Total Debt 290,640,000
Total Revenue 234,603,008
Tradeable 0
Trailing Annual Dividend Rate 0.0
Trailing Annual Dividend Yield 0.0
Trailing Eps -0.46
Trailing Peg Ratio None
Triggerable 1
Two Hundred Day Average 39.812473
Two Hundred Day Average Change 27.697529
Two Hundred Day Average Change Percent 0.69569975
Type Disp Equity
Volume 621,101
Website https://www.anaptysbio.com
Zip 92,121-5801