Amylyx Pharmaceuticals, Inc. (AMLX)Healthcare | Drug Manufacturers - Specialty & Generic | Cambridge, United States | NasdaqGS
34.74 USD
-2.44
(-6.563%) ⇩
(Aug. 28, 2026, 4 p.m.
EDT)
After hours: 34.85 +0.11 (0.317%) ⇧ (Aug. 28, 2026, 7:41 p.m. EDT) |
Hot Take ↕ | Aug. 22, 2026, 4:15 a.m. EDT
The immediate narrative here is a classic 'dead cat bounce' turning into a speculative rally. After a catastrophic collapse from $93 in 2024 to roughly $2 in 2024, the stock staged a miraculous recovery to the high $30s in late August, erasing nearly all losses in a matter of weeks. This isn't driven by a turnaround in fundamentals—the company remains unprofitable with negative free cash flow and a negative forward P/E—so the move is purely speculative. However, the options market is screaming bullishness, with traders buying calls at strikes that would require a 30-50% gain from current levels, while almost no one is hedging with puts. This asymmetry suggests a high-risk, high-reward momentum play rather than a value investment. The statistical forecast model offers a weak lean upward, which aligns with the options flow but lacks the conviction to stand alone against the fundamental reality of the business. For investors, this is a binary bet on whether the Avexitide catalyst can drive a sustained re-rating, or if the recent surge was a final liquidation event. Given the lack of dividends and weak long-term earnings trajectory, this is strictly a short-to-intermediate term momentum trade, not a buy-and-hold opportunity. |
| Model | MAE |
|---|---|
| AutoETS ✓ | 0.160200 |
| AutoARIMA | 0.160356 |
| AutoTheta | 0.172159 |
| MSTL | 0.207206 |
Forecast horizon: 45 days | Selected: AutoETS
| Forecast Reliability | |
|---|---|
| Score | 20% |
| H-stat | 149.17 |
| Ljung-Box p | 0.000 |
| Jarque-Bera p | 0.002 |
| Excess Kurtosis | 0.02 |
| Attribute | Value |
|---|---|
| Sector | Healthcare |
| Debt to Equity Ratio | 2.197 |
| Market Cap | 3,870,836,992 |
| Forward P/E | -30.09 |
| Beta | -0.21 |
| Website | https://amylyx.com |
As of Aug. 22, 2026, 4:15 a.m. EDT: Speculators are aggressively positioning for a massive upside breakout, evidenced by heavy call volume at strikes significantly above the current price (e.g., $29, $35, $40) and a distinct lack of put writing beyond deep out-of-the-money levels. The implied volatility surface shows elevated premiums for near-term calls relative to the underlying's recent range, suggesting a 'long gamma' setup where traders expect a sharp move higher. Conversely, the put side is nearly dormant except for deep OTM hedges, indicating a consensus view that downside risk is limited or priced in via the recent crash.
| Attribute | Value |
|---|---|
| 52 Week Change | 2.725451 |
| Address1 | 55 Cambridge Parkway |
| Address2 | Suite 6W |
| All Time High | 41.93 |
| All Time Low | 1.575 |
| Ask | 34.62 |
| Ask Size | 1 |
| Audit Risk | 6 |
| Average Analyst Rating | 1.2 - Strong Buy |
| Average Daily Volume10 Day | 5,894,530 |
| Average Daily Volume3 Month | 2,436,477 |
| Average Volume | 2,460,874 |
| Average Volume10Days | 5,894,530 |
| Beta | -0.205 |
| Bid | 35.16 |
| Bid Size | 2 |
| Board Risk | 7 |
| Book Value | 2.148 |
| City | Cambridge |
| Compensation As Of Epoch Date | 1,767,139,200 |
| Compensation Risk | 8 |
| Country | United States |
| Crypto Tradeable | 0 |
| Currency | USD |
| Current Price | 34.74 |
| Current Ratio | 12.12 |
| Custom Price Alert Confidence | HIGH |
| Date Short Interest | 1,786,665,600 |
| Day High | 37.68 |
| Day Low | 34.475 |
| Debt To Equity | 2.197 |
| Display Name | Amylyx Pharmaceuticals |
| Earnings Call Timestamp End | 1,786,017,600 |
| Earnings Call Timestamp Start | 1,786,017,600 |
| Earnings Timestamp | 1,786,019,400 |
| Earnings Timestamp End | 1,793,881,800 |
| Earnings Timestamp Start | 1,793,881,800 |
| Ebitda | -161,734,000 |
| Ebitda Margins | 0.0 |
| Enterprise To Ebitda | -24.096 |
| Enterprise Value | 3,897,203,968 |
| Eps Current Year | -1.49716 |
| Eps Forward | -1.15469 |
| Eps Trailing Twelve Months | -1.41 |
| Esg Populated | 0 |
| Exchange | NMS |
| Exchange Data Delayed By | 0 |
| Exchange Timezone Name | America/New_York |
| Exchange Timezone Short Name | EDT |
| Fifty Day Average | 22.0896 |
| Fifty Day Average Change | 12.650402 |
| Fifty Day Average Change Percent | 0.5726859 |
| Fifty Two Week Change Percent | 296.37527 |
| Fifty Two Week High | 41.14 |
| Fifty Two Week High Change | -6.3999977 |
| Fifty Two Week High Change Percent | -0.1555663 |
| Fifty Two Week Low | 9.145 |
| Fifty Two Week Low Change | 25.595001 |
| Fifty Two Week Low Change Percent | 2.7987971 |
| Fifty Two Week Range | 9.145 - 41.14 |
| Financial Currency | USD |
| First Trade Date Milliseconds | 1,641,565,800,000 |
| Float Shares | 97,214,381 |
| Forward Eps | -1.15469 |
| Forward P E | -30.085999 |
| Free Cashflow | -77,316,376 |
| Full Exchange Name | NasdaqGS |
| Full Time Employees | 136 |
| Fullday Change | -2.44 |
| Fullday Change Percent | -6.56266 |
| Fullday Price | 34.85 |
| Gmt Off Set Milliseconds | -14,400,000 |
| Governance Epoch Date | 1,785,542,400 |
| Gross Margins | 0.0 |
| Gross Profits | -90,849,000 |
| Has Pre Post Market Data | 1 |
| Held Percent Insiders | 0.07141 |
| Held Percent Institutions | 0.93795997 |
| Implied Shares Outstanding | 111,423,048 |
| Industry | Drug Manufacturers - Specialty & Generic |
| Industry Disp | Drug Manufacturers - Specialty & Generic |
| Industry Key | drug-manufacturers-specialty-generic |
| Ipo Expected Date | 2,022-01-07 |
| Is Earnings Date Estimate | 0 |
| Language | en-US |
| Last Fiscal Year End | 1,767,139,200 |
| Long Business Summary | Amylyx Pharmaceuticals, Inc., a clinical-stage pharmaceutical company, engages in the discovery and development of treatment options for neurodegenerative diseases and endocrine conditions in the United States. It provides Avexitide, an investigational, first-in-class glucagon-like peptide-1, or GLP-1 receptor antagonist, which is in phase 3 clinical trial to treat post-bariatric hypoglycemia and congenital hyperinsulinism. The company also develops AMX0035, an oral, fixed-dose combination of sodium phenylbutyrate and taurursodiol which is phase 2 clinical trial for the treatment of wolfram syndrome, as well as in phase 2b/3 clinical trial to treat progressive supranuclear palsy; AMX0114, which is in phase 1 clinical trial for the treatment of amyotrophic lateral sclerosis; and long-acting GLP-1 receptor antagonist to treat post-bariatric hypoglycemia and other rare diseases. Further, it develops AMX0318, a GLP-1 receptor antagonist for the treatment of post-bariatric hypoglycemia and other rare diseaees. Amylyx Pharmaceuticals, Inc. was founded in 2013 and is headquartered in Cambridge, Massachusetts. |
| Long Name | Amylyx Pharmaceuticals, Inc. |
| Market | us_market |
| Market Cap | 3,870,836,992 |
| Market State | CLOSED |
| Max Age | 86,400 |
| Message Board Id | finmb_317169670 |
| Most Recent Quarter | 1,782,777,600 |
| Net Income To Common | -152,092,000 |
| Next Fiscal Year End | 1,798,675,200 |
| Non Diluted Market Cap | 4,140,480,463 |
| Number Of Analyst Opinions | 11 |
| Open | 36.78 |
| Operating Cashflow | -126,577,000 |
| Operating Margins | 0.0 |
| Overall Risk | 8 |
| Payout Ratio | 0.0 |
| Phone | 617 682 0917 |
| Post Market Change | 0.109996796 |
| Post Market Change Percent | 0.31662863 |
| Post Market Price | 34.85 |
| Post Market Time | 1,787,960,494 |
| Previous Close | 37.18 |
| Price Eps Current Year | -23.203934 |
| Price Hint | 2 |
| Price To Book | 16.173185 |
| Profit Margins | 0.0 |
| Quick Ratio | 11.88 |
| Quote Source Name | Nasdaq Real Time Price |
| Quote Type | EQUITY |
| Recommendation Key | strong_buy |
| Recommendation Mean | 1.16667 |
| Region | US |
| Regular Market Change | -2.44 |
| Regular Market Change Percent | -6.56266 |
| Regular Market Day High | 37.68 |
| Regular Market Day Low | 34.475 |
| Regular Market Day Range | 34.475 - 37.68 |
| Regular Market Open | 36.78 |
| Regular Market Previous Close | 37.18 |
| Regular Market Price | 34.74 |
| Regular Market Time | 1,787,947,201 |
| Regular Market Volume | 1,361,345 |
| Return On Assets | -0.4413 |
| Return On Equity | -0.7473 |
| Sand P52 Week Change | 0.1966995 |
| Sector | Healthcare |
| Sector Disp | Healthcare |
| Sector Key | healthcare |
| Share Holder Rights Risk | 8 |
| Shares Outstanding | 111,423,048 |
| Shares Percent Shares Out | 0.1205 |
| Shares Short | 13,425,106 |
| Shares Short Previous Month Date | 1,784,073,600 |
| Shares Short Prior Month | 12,265,993 |
| Short Name | Amylyx Pharmaceuticals, Inc. |
| Short Percent Of Float | 0.1558 |
| Short Ratio | 7.01 |
| Source Interval | 15 |
| State | MA |
| Symbol | AMLX |
| Target High Price | 57.0 |
| Target Low Price | 20.0 |
| Target Mean Price | 42.36364 |
| Target Median Price | 42.0 |
| Total Cash | 250,760,000 |
| Total Cash Per Share | 2.251 |
| Total Debt | 5,255,000 |
| Tradeable | 0 |
| Trailing Annual Dividend Rate | 0.0 |
| Trailing Annual Dividend Yield | 0.0 |
| Trailing Eps | -1.41 |
| Trailing Peg Ratio | None |
| Triggerable | 1 |
| Two Hundred Day Average | 16.22565 |
| Two Hundred Day Average Change | 18.51435 |
| Two Hundred Day Average Change Percent | 1.1410544 |
| Type Disp | Equity |
| Volume | 1,361,345 |
| Website | https://amylyx.com |
| Zip | 2,142 |