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Alumis Inc. (ALMS)

Healthcare | Biotechnology | South San Francisco, United States | NasdaqGS
24.99 USD -0.01 (-0.040%) ⇩ (April 17, 2026, 4 p.m. EDT)
After hours: 24.91 -0.08 (-0.080%) ⇩ (April 17, 2026, 6:03 p.m. EDT)

Short-term: ★★★★☆ | Long-term: ★★☆☆☆ | Dividends: ☆☆☆☆☆
Hot Take | April 18, 2026, 2:14 p.m. EDT

Analyst upgrades and clinical progress fuel short-term bullish momentum, but high debt, negative earnings, and weak fundamentals create long-term risks.

Model Selection — Backtest MAE (log-scale, lower is better)
ModelMAE
AutoTheta ✓0.900410
AutoARIMA0.926304
AutoETS0.931649
MSTL0.958383

Forecast horizon: 45 days | Selected: AutoTheta

Forecast Reliability
Score 42%
H-stat 25.88
Ljung-Box p 0.000
Jarque-Bera p 0.168
Excess Kurtosis -1.36
Attribute Value
Sector Healthcare
Debt to Equity Ratio 12.252
Revenue per Share 0.283
Market Cap 3,178,711,296
Forward P/E -7.73
Website https://www.alumis.com

As of April 18, 2026, 2:14 p.m. EDT: Calls show elevated OTM positioning (29.0, 40.0) with new flow and higher IV, suggesting bullish speculation. Puts have OTM activity but low ATM volume. July 17 expiration features a major OI wall at 40.0, while May 15 shows ATM anchor at 25.0. Mixed sentiment with bullish calls outpacing bearish puts.


Info Dump

Attribute Value
52 Week Change 4.3170214
Address1 280 East Grand Avenue
All Time High 30.6
All Time Low 2.76
Ask 25.11
Ask Size 1
Audit Risk 7
Average Analyst Rating 1.1 - Strong Buy
Average Daily Volume10 Day 1,236,190
Average Daily Volume3 Month 1,541,711
Average Volume 1,541,711
Average Volume10Days 1,236,190
Bid 24.9
Bid Size 2
Board Risk 8
Book Value 2.878
City South San Francisco
Compensation As Of Epoch Date 1,767,139,200
Compensation Risk 9
Country United States
Crypto Tradeable 0
Currency USD
Current Price 24.99
Current Ratio 4.34
Custom Price Alert Confidence HIGH
Date Short Interest 1,774,915,200
Day High 25.91
Day Low 24.89
Debt To Equity 12.252
Display Name Alumis
Earnings Timestamp 1,773,950,400
Earnings Timestamp End 1,778,875,200
Earnings Timestamp Start 1,778,875,200
Ebitda -438,408,000
Ebitda Margins 0.0
Enterprise To Ebitda -6.631
Enterprise To Revenue 120.878
Enterprise Value 2,907,124,224
Eps Current Year -3.06
Eps Forward -3.23333
Eps Trailing Twelve Months -2.86
Esg Populated 0
Exchange NMS
Exchange Data Delayed By 0
Exchange Timezone Name America/New_York
Exchange Timezone Short Name EDT
Fifty Day Average 25.6829
Fifty Day Average Change -0.6928997
Fifty Day Average Change Percent -0.02697903
Fifty Two Week Change Percent 431.70215
Fifty Two Week High 30.6
Fifty Two Week High Change -5.6100006
Fifty Two Week High Change Percent -0.18333335
Fifty Two Week Low 2.76
Fifty Two Week Low Change 22.23
Fifty Two Week Low Change Percent 8.054348
Fifty Two Week Range 2.76 - 30.6
Financial Currency USD
First Trade Date Milliseconds 1,719,581,400,000
Float Shares 84,990,778
Forward Eps -3.23333
Forward P E -7.7288737
Free Cashflow -202,334,000
Full Exchange Name NasdaqGS
Full Time Employees 221
Gmt Off Set Milliseconds -14,400,000
Governance Epoch Date 1,775,001,600
Gross Margins 1.0
Gross Profits 24,050,000
Has Pre Post Market Data 1
Held Percent Insiders 0.00617
Held Percent Institutions 0.76903
Implied Shares Outstanding 127,199,333
Industry Biotechnology
Industry Disp Biotechnology
Industry Key biotechnology
Ipo Expected Date 2,024-06-28
Is Earnings Date Estimate 1
Language en-US
Last Fiscal Year End 1,767,139,200
Long Business Summary Alumis Inc., a clinical stage biopharmaceutical company, focuses on the development and commercialization of medicines for autoimmune disorders. The company offers envudeucitinib, a tyrosine kinase 2 (TYK2) inhibitor for the treatment of plaque psoriasis and systemic lupus erythematosus; and A-005, a central nervous system-penetrant allosteric TYK2 inhibitor that is in Phase 1 for the treatment of neuroinflammatory and neurodegenerative diseases. It also develops lonigutamab, a monoclonal antibody targeting IGF-1R for the treatment of thyroid eye diseases; and interferon regulatory factor 5 (IRF5) to address immune dysfunction. The company was formerly known as Esker Therapeutics, Inc. and changed its name to Alumis Inc. in January 2022. Alumis Inc. was incorporated in 2021 and is headquartered in South San Francisco, California.
Long Name Alumis Inc.
Market us_market
Market Cap 3,178,711,296
Market State CLOSED
Max Age 86,400
Message Board Id finmb_705657695
Most Recent Quarter 1,767,139,200
Net Income To Common -243,324,992
Next Fiscal Year End 1,798,675,200
Non Diluted Market Cap 3,178,711,330
Number Of Analyst Opinions 10
Open 25.75
Operating Cashflow -369,523,008
Operating Margins -50.67133
Overall Risk 10
Payout Ratio 0.0
Phone 650 231 6625
Post Market Change -0.07999992
Post Market Change Percent -0.32012776
Post Market Price 24.91
Post Market Time 1,776,463,391
Previous Close 25.0
Price Eps Current Year -8.166667
Price Hint 2
Price To Book 8.683113
Price To Sales Trailing12 Months 132.17094
Profit Margins 0.0
Quick Ratio 4.236
Quote Source Name Nasdaq Real Time Price
Quote Type EQUITY
Recommendation Key strong_buy
Recommendation Mean 1.09091
Region US
Regular Market Change -0.0100002
Regular Market Change Percent -0.0400009
Regular Market Day High 25.91
Regular Market Day Low 24.89
Regular Market Day Range 24.89 - 25.91
Regular Market Open 25.75
Regular Market Previous Close 25.0
Regular Market Price 24.99
Regular Market Time 1,776,456,001
Regular Market Volume 1,156,523
Return On Assets -0.73363996
Return On Equity -0.86684996
Revenue Per Share 0.283
Sand P52 Week Change 0.38150132
Sector Healthcare
Sector Disp Healthcare
Sector Key healthcare
Share Holder Rights Risk 10
Shares Outstanding 123,139,425
Shares Percent Shares Out 0.0883
Shares Short 11,230,693
Shares Short Previous Month Date 1,772,150,400
Shares Short Prior Month 7,953,241
Short Name Alumis Inc.
Short Percent Of Float 0.1612
Short Ratio 6.69
Source Interval 15
State CA
Symbol ALMS
Target High Price 55.0
Target Low Price 25.0
Target Mean Price 38.4
Target Median Price 38.0
Total Cash 308,500,992
Total Cash Per Share 2.425
Total Debt 36,914,000
Total Revenue 24,050,000
Tradeable 0
Trailing Annual Dividend Rate 0.0
Trailing Annual Dividend Yield 0.0
Trailing Eps -2.86
Trailing Peg Ratio None
Triggerable 1
Two Hundred Day Average 12.554975
Two Hundred Day Average Change 12.435025
Two Hundred Day Average Change Percent 0.9904461
Type Disp Equity
Volume 1,156,523
Website https://www.alumis.com
Zip 94,080