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Agenus Inc. (AGEN)

Healthcare | Biotechnology | Lexington, United States | NasdaqCM
7.66 USD -0.15 (-1.921%) ⇩ (Aug. 28, 2026, 4 p.m. EDT)
After hours: 7.66

Short-term:★★⯪☆☆Long-term:★☆☆☆☆Dividends:☆☆☆☆☆
Hot Take | Aug. 22, 2026, 2:50 a.m. EDT

The investment case here is severely compromised by a brutal multi-year decline. Despite a recent surge in stock price and positive headlines regarding financing, the underlying business has suffered four consecutive years of negative annual returns, dropping nearly 96% over the last nine years. This structural deterioration outweighs the current positive momentum and the optimistic analyst targets, which likely reflect a binary event-driven thesis rather than sustainable operational recovery. The options market confirms this fear, with traders aggressively buying protection at lower price levels while offering very little upside exposure. Without a clear turnaround in the revenue trajectory, the stock remains a high-risk speculative vehicle rather than a viable long-term holding.

Model Selection — Backtest MAE (log-scale, lower is better)
ModelMAE
MSTL ✓0.323171
AutoETS0.325412
AutoARIMA0.325414
AutoTheta0.326856

Forecast horizon: 45 days | Selected: MSTL

Forecast Reliability
Score 24%
H-stat 134.39
Ljung-Box p 0.000
Jarque-Bera p 0.068
Excess Kurtosis -1.40
Attribute Value
Sector Healthcare
Revenue per Share 3.645
Market Cap 344,774,080
Trailing P/E 2.61
Forward P/E -127.67
Beta 1.40
Profit Margins 69.34%
Website https://www.agenusbio.com

As of Aug. 22, 2026, 2:50 a.m. EDT: Speculators are heavily positioning for downside protection, evidenced by massive open interest in out-of-the-money puts (strikes 4.0, 5.0, 6.0) compared to negligible call volume. While there is some activity in deep in-the-money calls, the overwhelming capital allocation is in put writing and buying, suggesting a consensus expectation of further price weakness rather than a rally.


Info Dump

Attribute Value
52 Week Change 0.84134614
Address1 3 Forbes Road
All Time High 7,065.751
All Time Low 1.38
Ask 9.83
Ask Size 2
Average Analyst Rating 1.0 - Strong Buy
Average Daily Volume10 Day 1,143,700
Average Daily Volume3 Month 4,193,053
Average Volume 4,193,053
Average Volume10Days 1,143,700
Beta 1.396
Bid 5.77
Bid Size 2
Book Value -4.671
City Lexington
Compensation As Of Epoch Date 1,672,444,800
Country United States
Crypto Tradeable 0
Currency USD
Current Price 7.66
Current Ratio 0.34
Custom Price Alert Confidence HIGH
Date Short Interest 1,786,665,600
Day High 8.07
Day Low 7.6137
Display Name Agenus
Earnings Call Timestamp End 1,747,053,000
Earnings Call Timestamp Start 1,747,053,000
Earnings Timestamp 1,786,019,400
Earnings Timestamp End 1,793,881,800
Earnings Timestamp Start 1,793,881,800
Ebitda 40,610,000
Ebitda Margins 0.30604
Enterprise To Ebitda 8.866
Enterprise To Revenue 2.713
Enterprise Value 360,051,328
Eps Current Year 0.87
Eps Forward -0.06
Eps Trailing Twelve Months 2.94
Esg Populated 0
Exchange NCM
Exchange Data Delayed By 0
Exchange Timezone Name America/New_York
Exchange Timezone Short Name EDT
Fax 781 674 4200
Fifty Day Average 5.7742
Fifty Day Average Change 1.8857999
Fifty Day Average Change Percent 0.3265907
Fifty Two Week Change Percent 84.13461
Fifty Two Week High 8.85
Fifty Two Week High Change -1.1900005
Fifty Two Week High Change Percent -0.13446333
Fifty Two Week Low 2.71
Fifty Two Week Low Change 4.95
Fifty Two Week Low Change Percent 1.8265681
Fifty Two Week Range 2.71 - 8.85
Financial Currency USD
First Trade Date Milliseconds 950,020,200,000
Float Shares 40,236,989
Forward Eps -0.06
Forward P E -127.666664
Free Cashflow -74,785,872
Full Exchange Name NasdaqCM
Full Time Employees 81
Fullday Change -0.15
Fullday Change Percent -1.92062
Fullday Price 7.66
Gmt Off Set Milliseconds -14,400,000
Gross Margins 1.13608
Gross Profits 150,750,000
Has Pre Post Market Data 1
Held Percent Insiders 0.06229
Held Percent Institutions 0.45948002
Implied Shares Outstanding 45,009,670
Industry Biotechnology
Industry Disp Biotechnology
Industry Key biotechnology
Ir Website http://www.agenusbio.com/investors/performance.shtml
Is Earnings Date Estimate 1
Language en-US
Last Fiscal Year End 1,767,139,200
Last Split Date 1,712,880,000
Last Split Factor 1:20
Long Business Summary Agenus Inc., a clinical-stage biotechnology company, discovers and develops immunotherapies for cancer and infectious diseases in the United States and internationally. It offers Retrocyte Display, an antibody expression platform for the identification of fully human and humanized monoclonal antibodies; and display technologies. It develops QS-21 Stimulon adjuvant, a saponin-based vaccine adjuvant. The company also develops Balstilimab, a programmed death receptor-1 (PD-1) blocking antibody; AGEN1181, a human Fc-enhanced cytotoxic T-lymphocyte antigen 4 (CTLA-4) blocking antibody that is in Phase 2 trials in metastatic colorectal cancer (mCRC), pancreatic cancer, and melanoma; AGEN2373, a CD137 monospecific antibody that is in Phase 1b clinical trial; AGEN1423, a CD73/TGFß TRAP antibody; AGEN1571, an ILT2 monospecific antibody that is in clinical development; and BMS-986442, a TIGIT bispecific antibodies. In addition, it develops INCAGN1876, a GITR agonist; INCAGN2390, a TIM-3 monoclonal antibodies; INCAGN2385, a LAG-3 monospecific antibody; MK-4830, a monospecific antibody targeting ILT4 that is in Phase 2 clinical trial; and AGEN1884. The company operates under the Agenus, MiNK, Prophage, Retrocyte Display, and STIMULON trademarks. It has collaborations with Bristol-Myers Squibb Company, Betta Pharmaceuticals Co., Ltd., UroGen Pharma Ltd., Gilead Sciences, Inc., Incyte Corporation, and Merck Sharp & Dohme. The company was formerly known as Antigenics Inc. and changed its name to Agenus Inc. in January 2011. Agenus Inc. was founded in 1994 and is headquartered in Lexington, Massachusetts.
Long Name Agenus Inc.
Market us_market
Market Cap 344,774,080
Market State CLOSED
Max Age 86,400
Message Board Id finmb_409956
Most Recent Quarter 1,782,777,600
Net Income To Common 91,795,000
Next Fiscal Year End 1,798,675,200
Non Diluted Market Cap 351,075,426
Number Of Analyst Opinions 2
Open 7.98
Operating Cashflow -98,504,000
Operating Margins 0.32716
Payout Ratio 0.0
Peg Ratio 1.44
Phone 781 674 4400
Post Market Change 0.0
Post Market Change Percent 0.0
Post Market Price 7.66
Post Market Time 1,787,960,326
Previous Close 7.81
Price Eps Current Year 8.804598
Price Hint 2
Price To Book -1.6399058
Price To Sales Trailing12 Months 2.5982838
Profit Margins 0.69342005
Quick Ratio 0.319
Quote Source Name Nasdaq Real Time Price
Quote Type EQUITY
Recommendation Key none
Region US
Regular Market Change -0.15
Regular Market Change Percent -1.92062
Regular Market Day High 8.07
Regular Market Day Low 7.6137
Regular Market Day Range 7.6137 - 8.07
Regular Market Open 7.98
Regular Market Previous Close 7.81
Regular Market Price 7.66
Regular Market Time 1,787,947,201
Regular Market Volume 740,355
Return On Assets 0.12532
Revenue Growth 0.344
Revenue Per Share 3.645
Sand P52 Week Change 0.20204377
Sector Healthcare
Sector Disp Healthcare
Sector Key healthcare
Shares Outstanding 45,009,670
Shares Percent Shares Out 0.1303
Shares Short 5,863,005
Shares Short Previous Month Date 1,784,073,600
Shares Short Prior Month 7,057,525
Short Name Agenus Inc.
Short Percent Of Float 0.1318
Short Ratio 2.54
Source Interval 15
State MA
Symbol AGEN
Target High Price 25.0
Target Low Price 14.0
Target Mean Price 19.5
Target Median Price 19.5
Total Cash 18,738,000
Total Cash Per Share 0.416
Total Debt 40,708,000
Total Revenue 132,693,000
Tradeable 0
Trailing Annual Dividend Rate 0.0
Trailing Annual Dividend Yield 0.0
Trailing Eps 2.94
Trailing P E 2.605442
Trailing Peg Ratio None
Triggerable 1
Two Hundred Day Average 4.13505
Two Hundred Day Average Change 3.52495
Two Hundred Day Average Change Percent 0.8524565
Type Disp Equity
Volume 740,355
Website https://www.agenusbio.com
Zip 02,421-7305