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Adaptive Biotechnologies Corporation (ADPT)

Healthcare | Diagnostics & Research | Seattle, United States | NasdaqGS
26.44 USD +0.28 (1.070%) ⇧ (Aug. 27, 2026, 4 p.m. EDT)
After hours: 26.80 +0.36 (1.362%) ⇧ (Aug. 27, 2026, 7:41 p.m. EDT)

Short-term:★★⯪☆☆Long-term:★☆☆☆☆Dividends:☆☆☆☆☆
Hot Take | Aug. 22, 2026, 2:25 a.m. EDT

The long-term investment case is severely compromised by a brutal six-year price trajectory that erased over 70% of shareholder value, driven by five consecutive years of negative annual returns. Despite a massive 195% rebound in the most recent year, the underlying business remains unprofitable with negative operating margins and a forward P/E that is mathematically undefined due to losses. The balance sheet is fragile, carrying debt nearly equal to its cash reserves while generating negative operating cash flow. While the stock recently rallied on a business split announcement, the fundamental reality of a loss-making biotech firm with no dividend history makes it a speculative gamble rather than an investment. The short-term outlook is neutral at best; the statistical forecast offers only a weak lean upward, which is insufficient to overcome the structural risks of the business model and the lingering threat of further downside given the high beta and insider selling activity.

Model Selection — Backtest MAE (log-scale, lower is better)
ModelMAE
AutoTheta ✓0.241733
AutoARIMA0.254459
AutoETS0.278209
MSTL0.285105

Forecast horizon: 45 days | Selected: AutoTheta

Forecast Reliability
Score 33%
H-stat 9.17
Ljung-Box p 0.000
Jarque-Bera p 0.113
Excess Kurtosis -0.99
Attribute Value
Sector Healthcare
Debt to Equity Ratio 272.464
Revenue per Share 1.984
Market Cap 4,219,714,048
Forward P/E -143.13
Beta 2.09
Profit Margins -20.73%
Website https://www.adaptivebiotech.com

As of Aug. 22, 2026, 2:25 a.m. EDT: Speculators are positioning defensively with heavy out-of-the-money put volume relative to calls, creating a 'bear put' skew where protection is priced significantly higher than upside speculation. Open interest is concentrated deep in-the-money at strikes like $15 and $22.50, suggesting a floor expectation rather than a breakout thesis. The lack of significant call open interest above current prices indicates a lack of aggressive bullish positioning.


Info Dump

Attribute Value
52 Week Change 1.0060699
Address1 1,165 Eastlake Avenue East
All Time High 71.25
All Time Low 2.28
Ask 26.65
Ask Size 1
Audit Risk 3
Average Analyst Rating 1.5 - Strong Buy
Average Daily Volume10 Day 1,846,560
Average Daily Volume3 Month 2,954,612
Average Volume 2,954,612
Average Volume10Days 1,846,560
Beta 2.088
Bid 19.11
Bid Size 2
Board Risk 8
Book Value 0.898
City Seattle
Compensation As Of Epoch Date 1,767,139,200
Compensation Risk 5
Country United States
Crypto Tradeable 0
Currency USD
Current Price 26.44
Current Ratio 4.795
Custom Price Alert Confidence HIGH
Date Short Interest 1,786,665,600
Day High 26.87
Day Low 26.11
Debt To Equity 272.464
Display Name Adaptive Biotechnologies
Earnings Call Timestamp End 1,785,357,000
Earnings Call Timestamp Start 1,785,357,000
Earnings Timestamp 1,785,355,200
Earnings Timestamp End 1,793,822,400
Earnings Timestamp Start 1,793,822,400
Ebitda -21,327,000
Ebitda Margins -0.06923
Enterprise To Ebitda -201.327
Enterprise To Revenue 13.937
Enterprise Value 4,293,705,984
Eps Current Year -0.54108
Eps Forward -0.18473
Eps Trailing Twelve Months -0.4
Esg Populated 0
Exchange NMS
Exchange Data Delayed By 0
Exchange Timezone Name America/New_York
Exchange Timezone Short Name EDT
Fax 206 659 0667
Fifty Day Average 22.673
Fifty Day Average Change 3.7670002
Fifty Day Average Change Percent 0.16614476
Fifty Two Week Change Percent 100.60699
Fifty Two Week High 26.87
Fifty Two Week High Change -0.4300003
Fifty Two Week High Change Percent -0.016002988
Fifty Two Week Low 12.0
Fifty Two Week Low Change 14.440001
Fifty Two Week Low Change Percent 1.2033334
Fifty Two Week Range 12.0 - 26.87
Financial Currency USD
First Trade Date Milliseconds 1,561,642,200,000
Float Shares 125,463,079
Forward Eps -0.18473
Forward P E -143.12782
Free Cashflow 18,976,624
Full Exchange Name NasdaqGS
Full Time Employees 624
Fullday Change 0.280001
Fullday Change Percent 1.07034
Fullday Price 26.8
Gmt Off Set Milliseconds -14,400,000
Governance Epoch Date 1,785,542,400
Gross Margins 0.46942002
Gross Profits 144,619,008
Has Pre Post Market Data 1
Held Percent Insiders 0.01306
Held Percent Institutions 0.99244004
Implied Shares Outstanding 159,595,842
Industry Diagnostics & Research
Industry Disp Diagnostics & Research
Industry Key diagnostics-research
Is Earnings Date Estimate 1
Language en-US
Last Fiscal Year End 1,767,139,200
Long Business Summary Adaptive Biotechnologies Corporation, a commercial-stage company, develops an immune medicine platform for the diagnosis and treatment of various diseases. The company offers immunosequencing platform which combines a suite of proprietary chemistry, computational biology, and machine learning to generate clinical immunomics data to decode the adaptive immune system. It provides clonoSEQ diagnostic test which detects and monitors the remaining number of cancer cells that are present in a patient's body during and after treatment, known as Minimal Residual Disease (MRD). The company offers products and services for life sciences research, clinical diagnostics, and drug discovery applications. The company was formerly known as Adaptive TCR Corporation and changed its name to Adaptive Biotechnologies Corporation in December 2011. Adaptive Biotechnologies Corporation was incorporated in 2009 and is headquartered in Seattle, Washington.
Long Name Adaptive Biotechnologies Corporation
Market us_market
Market Cap 4,219,714,048
Market State PREPRE
Max Age 86,400
Message Board Id finmb_100147173
Most Recent Quarter 1,782,777,600
Net Income To Common -63,854,000
Next Fiscal Year End 1,798,675,200
Non Diluted Market Cap 4,175,027,226
Number Of Analyst Opinions 7
Open 26.23
Operating Cashflow -21,009,000
Operating Margins -0.2204
Overall Risk 7
Payout Ratio 0.0
Phone 206 659 0067
Post Market Change 0.3599987
Post Market Change Percent 1.3615685
Post Market Price 26.8
Post Market Time 1,787,874,076
Previous Close 26.16
Price Eps Current Year -48.865234
Price Hint 2
Price To Book 29.443207
Price To Sales Trailing12 Months 13.696769
Profit Margins -0.20726
Quick Ratio 4.51
Quote Source Name Nasdaq Real Time Price
Quote Type EQUITY
Recommendation Key strong_buy
Recommendation Mean 1.5
Region US
Regular Market Change 0.280001
Regular Market Change Percent 1.07034
Regular Market Day High 26.87
Regular Market Day Low 26.11
Regular Market Day Range 26.11 - 26.87
Regular Market Open 26.23
Regular Market Previous Close 26.16
Regular Market Price 26.44
Regular Market Time 1,787,860,801
Regular Market Volume 1,944,008
Return On Assets -0.04117
Return On Equity -0.38759
Revenue Growth 0.215
Revenue Per Share 1.984
Sand P52 Week Change 0.1890428
Sector Healthcare
Sector Disp Healthcare
Sector Key healthcare
Share Holder Rights Risk 8
Shares Outstanding 159,595,842
Shares Percent Shares Out 0.083500005
Shares Short 13,323,767
Shares Short Previous Month Date 1,784,073,600
Shares Short Prior Month 11,396,387
Short Name Adaptive Biotechnologies Corpor
Short Percent Of Float 0.105500005
Short Ratio 4.98
Source Interval 15
State WA
Symbol ADPT
Target High Price 28.0
Target Low Price 21.0
Target Mean Price 25.07143
Target Median Price 25.0
Total Cash 344,255,008
Total Cash Per Share 2.157
Total Debt 410,499,008
Total Revenue 308,080,992
Tradeable 0
Trailing Annual Dividend Rate 0.0
Trailing Annual Dividend Yield 0.0
Trailing Eps -0.4
Trailing Peg Ratio None
Triggerable 1
Two Hundred Day Average 17.3708
Two Hundred Day Average Change 9.0692005
Two Hundred Day Average Change Percent 0.5220946
Type Disp Equity
Volume 1,944,008
Website https://www.adaptivebiotech.com
Zip 98,109