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Adagene Inc. (ADAG)

Healthcare | Biotechnology | Suzhou, China | NasdaqGM
3.68 USD -0.22 (-5.641%) ⇩ (Aug. 28, 2026, 4 p.m. EDT)
After hours: 3.68

Short-term:★★⯪☆☆Long-term:★☆☆☆☆Dividends:☆☆☆☆☆
Hot Take | Aug. 22, 2026, 4:15 a.m. EDT

The immediate outlook remains neutral due to conflicting signals: while the stock recently rallied off its lows, the underlying business fundamentals are severely deteriorating. The company is burning significant cash with negative operating and free cash flows, and the balance sheet shows a concerning debt-to-equity ratio despite holding some cash. Crucially, the multi-year price trajectory reveals a catastrophic decline of over 85%, driven by three consecutive years of negative annual returns, which suggests the market has permanently reassessed the business quality. Although analysts offer a 'strong buy' recommendation with a high target price, this appears to be a speculative bet on a potential turnaround rather than a reflection of current operational reality. With no dividend history and a history of massive losses, there is no safety net for investors.

Model Selection — Backtest MAE (log-scale, lower is better)
ModelMAE
AutoTheta ✓0.089251
MSTL0.092137
AutoETS0.096413
AutoARIMA0.096414

Forecast horizon: 45 days | Selected: AutoTheta

Forecast Reliability
Score 39%
H-stat 0.92
Ljung-Box p 0.000
Jarque-Bera p 0.375
Excess Kurtosis 0.08
Attribute Value
Sector Healthcare
Debt to Equity Ratio 5.746
Revenue per Share 0.179
Market Cap 247,087,504
Forward P/E -6.57
Beta 0.57
Profit Margins -220.77%
Website https://www.adagene.com

Info Dump

Attribute Value
52 Week Change 0.8396226
Address1 Building C14
Address2 4th Floor No. 218, Xinghu Street Suzhou Industrial Park
All Time High 31.83
All Time Low 0.9
Ask 4.0
Ask Size 3
Average Analyst Rating 1.3 - Strong Buy
Average Daily Volume10 Day 272,280
Average Daily Volume3 Month 269,662
Average Volume 269,662
Average Volume10Days 272,280
Beta 0.572
Bid 2.56
Bid Size 2
Book Value 1.332
City Suzhou
Country China
Crypto Tradeable 0
Currency USD
Current Price 3.68
Current Ratio 5.023
Custom Price Alert Confidence HIGH
Date Short Interest 1,786,665,600
Day High 3.8672
Day Low 3.66
Debt To Equity 5.746
Display Name Adagene
Earnings Timestamp End 1,753,704,000
Earnings Timestamp Start 1,753,268,340
Ebitda -21,952,354
Ebitda Margins -2.3628
Enterprise To Ebitda -6.46
Enterprise To Revenue 15.264
Enterprise Value 141,818,704
Eps Current Year -0.52
Eps Forward -0.56
Eps Trailing Twelve Months -0.37
Esg Populated 0
Exchange NGM
Exchange Data Delayed By 0
Exchange Timezone Name America/New_York
Exchange Timezone Short Name EDT
Fifty Day Average 3.873
Fifty Day Average Change -0.19299984
Fifty Day Average Change Percent -0.04983213
Fifty Two Week Change Percent 83.962265
Fifty Two Week High 4.85
Fifty Two Week High Change -1.1699998
Fifty Two Week High Change Percent -0.24123709
Fifty Two Week Low 1.3
Fifty Two Week Low Change 2.38
Fifty Two Week Low Change Percent 1.8307694
Fifty Two Week Range 1.3 - 4.85
Financial Currency USD
First Trade Date Milliseconds 1,612,881,000,000
Float Shares 42,170,720
Forward Eps -0.56
Forward P E -6.571429
Free Cashflow -12,158,853
Full Exchange Name NasdaqGM
Full Time Employees 128
Fullday Change -0.22
Fullday Change Percent -5.64103
Fullday Price 3.68
Gmt Off Set Milliseconds -14,400,000
Gross Margins 1.0
Gross Profits 9,290,815
Has Pre Post Market Data 1
Held Percent Insiders 0.21292
Held Percent Institutions 0.35937
Implied Shares Outstanding 67,143,344
Industry Biotechnology
Industry Disp Biotechnology
Industry Key biotechnology
Ipo Expected Date 2,021-02-09
Is Earnings Date Estimate 1
Language en-US
Last Fiscal Year End 1,767,139,200
Long Business Summary Adagene Inc., a clinical stage biotechnology company, engages in the research, development, and production of monoclonal antibody drugs for cancers in the People's Republic of China. Its lead product candidate is the ADG126, a masked fully-human anti-CTLA-4 mAb which is in phase 1b/2 clinical development for the treatment of cancer. The company also develops ADG116, a fully human anti-CTLA-4 antibody generated using NEObody technology, which is in phase 1b/2 clinical trials to treat advanced/metastatic solid tumors; ADG206, which is in phase 1 clinical development to treat advanced metastatic solid tumors; ADG104, anti-PD-L1 monoclonal antibody which is in phase 2 clinical development; and ADG125, a novel anti-CSF-1R mAb which is in Phase 2 clinical development. In addition, it is developing ADG138, a HER2xCD3 POWERbody which is in pre clinical trial to treat low expressing tumors, as well as resistant/refractory tumors; ADG152, a CD20xCD3 POWERbody which is in preclincal trial to treat off-tumor toxicities; ADG153, a masked anti-CD47 IgG1 SAFEbody, wihx is in preclinical trial for the treatment of hematologic and solid tumor; and CD28 T-cell engagers, an anti-CD28 bispecific POWERbody TCEs to treat solid tumors. Adagene Inc. was incorporated in 2011 and is headquartered in Suzhou, China.
Long Name Adagene Inc.
Market us_market
Market Cap 247,087,504
Market State CLOSED
Max Age 86,400
Message Board Id finmb_118162960
Most Recent Quarter 1,782,777,600
Net Income To Common -20,511,004
Next Fiscal Year End 1,798,675,200
Non Diluted Market Cap 262,530,475
Number Of Analyst Opinions 6
Open 3.86
Operating Cashflow -19,247,964
Operating Margins -10.23915
Payout Ratio 0.0
Phone 86 512 8777 3632
Post Market Change 0.0
Post Market Change Percent 0.0
Post Market Price 3.68
Post Market Time 1,787,959,804
Previous Close 3.9
Price Eps Current Year -7.0769234
Price Hint 4
Price To Book 2.7627628
Price To Sales Trailing12 Months 26.594814
Profit Margins -2.20766
Quick Ratio 4.858
Quote Source Name Nasdaq Real Time Price
Quote Type EQUITY
Recommendation Key strong_buy
Recommendation Mean 1.28571
Region US
Regular Market Change -0.22
Regular Market Change Percent -5.64103
Regular Market Day High 3.8672
Regular Market Day Low 3.66
Regular Market Day Range 3.66 - 3.8672
Regular Market Open 3.86
Regular Market Previous Close 3.9
Regular Market Price 3.68
Regular Market Time 1,787,947,201
Regular Market Volume 123,153
Return On Assets -0.13954
Return On Equity -0.28504
Revenue Per Share 0.179
Sand P52 Week Change 0.20504117
Sector Healthcare
Sector Disp Healthcare
Sector Key healthcare
Shares Outstanding 67,143,344
Shares Percent Shares Out 0.031400003
Shares Short 2,110,754
Shares Short Previous Month Date 1,784,073,600
Shares Short Prior Month 2,189,615
Short Name Adagene Inc.
Short Percent Of Float 0.0369
Short Ratio 9.49
Source Interval 15
Symbol ADAG
Target High Price 17.45
Target Low Price 7.0
Target Mean Price 10.74167
Target Median Price 9.0
Total Cash 127,909,840
Total Cash Per Share 1.905
Total Debt 6,091,037
Total Revenue 9,290,815
Tradeable 0
Trailing Annual Dividend Rate 0.0
Trailing Annual Dividend Yield 0.0
Trailing Eps -0.37
Trailing Peg Ratio None
Triggerable 1
Two Hundred Day Average 3.170735
Two Hundred Day Average Change 0.5092652
Two Hundred Day Average Change Percent 0.16061424
Type Disp Equity
Volume 123,153
Website https://www.adagene.com
Zip 215,123