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AC Immune SA (ACIU)

Healthcare | Biotechnology | Lausanne, Switzerland | NasdaqGM
3.01 USD -0.06 (-1.954%) ⇩ (April 17, 2026, 4 p.m. EDT)
After hours: 3.01

Short-term: ★★★★☆ | Long-term: ★★☆☆☆ | Dividends: ★☆☆☆☆
Hot Take | April 19, 2026, 12:55 a.m. EDT

Despite deteriorating fundamentals and_neg_1M sales, ACIU is experiencing a massive speculative divergence. The stock is decoupling from its earnings reality on the short end; while the P/E suggests a value trap and burn rate is high, the options flow is overwhelmingly bullish on a 2x price swing, driven likely by the positive news surrounding the Eli Lilly Tau program. This is a high-risk momentum trade riding a specific catalyst gap, not a fundamental value play.

Model Selection — Backtest MAE (log-scale, lower is better)
ModelMAE
AutoTheta ✓0.175707
AutoETS0.175797
AutoARIMA0.175874
MSTL0.181378

Forecast horizon: 45 days | Selected: AutoTheta

Forecast Reliability
Score 80%
H-stat 0.95
Ljung-Box p 0.000
Jarque-Bera p 0.768
Excess Kurtosis -0.50
Attribute Value
Sector Healthcare
Debt to Equity Ratio 10.117
Revenue per Share 0.035
Market Cap 306,338,464
Forward P/E 4.92
Beta 1.63
Website https://www.acimmune.com

As of April 19, 2026, 12:55 a.m. EDT: Call activity is heavily skewed strike-up, with significant Open Interest (OI) and volume concentrated at 5.0 and 7.5 level (OTM), suggesting bulls are positioning for a significant move to these levels (approx. +66% to +149% from ATM). Put OI is low, with notable interest only at deep OTM strikes for 2026-11-20 expiry. This gamma-side bias implies speculators are expecting a 100%+ rally relative to current price, while downside hedging is minimal.


Info Dump

Attribute Value
52 Week Change 1.0337837
Address1 Building B
Address2 EPFL Innovation Park
All Time High 19.97
All Time Low 1.43
Ask 3.05
Ask Size 1
Average Analyst Rating 1.0 - Strong Buy
Average Daily Volume10 Day 350,920
Average Daily Volume3 Month 297,995
Average Volume 297,995
Average Volume10Days 350,920
Beta 1.63
Bid 2.97
Bid Size 1
Book Value 0.5629806
City Lausanne
Compensation As Of Epoch Date 1,703,980,800
Country Switzerland
Crypto Tradeable 0
Currency USD
Current Price 3.01
Current Ratio 1.021
Custom Price Alert Confidence HIGH
Date Short Interest 1,774,915,200
Day High 3.16
Day Low 2.97
Debt To Equity 10.117
Earnings Timestamp 1,773,405,000
Earnings Timestamp End 1,777,465,800
Earnings Timestamp Start 1,777,465,800
Ebitda -67,470,000
Ebitda Margins 0.0
Enterprise To Ebitda -3.138
Enterprise To Revenue 59.257
Enterprise Value 211,724,464
Eps Current Year -0.4
Eps Forward 0.6122125
Eps Trailing Twelve Months -0.9
Esg Populated 0
Exchange NGM
Exchange Data Delayed By 0
Exchange Timezone Name America/New_York
Exchange Timezone Short Name EDT
Fax 41 21 345 91 20
Fifty Day Average 2.9341
Fifty Day Average Change 0.07590008
Fifty Day Average Change Percent 0.025868267
Fifty Two Week Change Percent 103.378365
Fifty Two Week High 4.0
Fifty Two Week High Change -0.99
Fifty Two Week High Change Percent -0.2475
Fifty Two Week Low 1.45
Fifty Two Week Low Change 1.56
Fifty Two Week Low Change Percent 1.075862
Fifty Two Week Range 1.45 - 4.0
Financial Currency CHF
First Trade Date Milliseconds 1,474,637,400,000
Float Shares 38,392,830
Forward Eps 0.6122125
Forward P E 4.9165936
Free Cashflow -41,761,752
Full Exchange Name NasdaqGM
Full Time Employees 90
Gmt Off Set Milliseconds -14,400,000
Gross Margins 0.0
Gross Profits -52,863,000
Has Pre Post Market Data 1
Held Percent Insiders 0.37893
Held Percent Institutions 0.25521
Implied Shares Outstanding 101,773,573
Industry Biotechnology
Industry Disp Biotechnology
Industry Key biotechnology
Is Earnings Date Estimate 1
Language en-US
Last Fiscal Year End 1,767,139,200
Long Business Summary AC Immune SA, a clinical stage biopharmaceutical company, discovers, designs, and develops medicines, and therapeutic and diagnostic products for the prevention and treatment of neurodegenerative diseases associated with protein misfolding. The company's SupraAntigen and Morphomer platforms are designed to generate biologics and small molecules, which selectively interact with misfolded proteins that are common in a range of neurodegenerative diseases. It develops Crenezumab, a humanized, conformation specific monoclonal antibody used to slow Alzheimer's disease (AD) progression; and Semorinemab, an investigational monoclonal anti-Tau antibody that targets the N-terminal portion of the Tau protein and is designed to bind to Tau and slow its spread between neurons for the treatment of AD. The company is also developing ACI-24.060 for the treatment of down syndrome related AD; ACI-7104.056 to treat Parkinson's disease; and ACI-35.030, designs to stimulate a patient's immune system to produce antibodies against pathological phosphorylated Tau. In addition, it develops diagnostic programs consisting of PI-2620, a Tau diagnostic for AD, as well as non-AD Tauopathies; and ACI-12589 and ACI-15916, a-sync PET tracer that supports the differential diagnosis of multiple system atrophy from other neurodegenerative diseases. Further, the company is researching and developing Morphomer Tau aggregation inhibitors to evaluate candidates in AD; Morphomer a-syn to compete with small molecule inhibitors of a-syn aggregation; and NeuroOrphan Tauopathies. Additionally, it generates discovery and preclinical stage molecules targeting range of neurodegenerative diseases, which include diagnostics targeting TDP-43, alpha-synuclein, and NLRP3. The company has license agreements and collaborations with Genentech, Inc.; Janssen Pharmaceuticals, Inc.; Life Molecular Imaging SA; and Eli Lilly and Company. AC Immune SA was incorporated in 2003 and is headquartered in Lausanne, Switzerland.
Long Name AC Immune SA
Market us_market
Market Cap 306,338,464
Market State CLOSED
Max Age 86,400
Message Board Id finmb_22309440
Most Recent Quarter 1,767,139,200
Net Income To Common -70,447,000
Next Fiscal Year End 1,798,675,200
Non Diluted Market Cap 305,320,719
Number Of Analyst Opinions 4
Open 3.12
Operating Cashflow -69,262,000
Operating Margins -42.6213
Payout Ratio 0.0
Phone 41 21 345 91 21
Post Market Change 0.0
Post Market Change Percent 0.0
Post Market Price 3.01
Post Market Time 1,776,456,604
Previous Close 3.07
Price Eps Current Year -7.525
Price Hint 4
Price To Book 5.3465433
Price To Sales Trailing12 Months 85.737045
Profit Margins 0.0
Quick Ratio 0.973
Quote Source Name Nasdaq Real Time Price
Quote Type EQUITY
Recommendation Key strong_buy
Recommendation Mean 1.0
Region US
Regular Market Change -0.0599999
Regular Market Change Percent -1.9544
Regular Market Day High 3.16
Regular Market Day Low 2.97
Regular Market Day Range 2.97 - 3.16
Regular Market Open 3.12
Regular Market Previous Close 3.07
Regular Market Price 3.01
Regular Market Time 1,776,456,001
Regular Market Volume 265,057
Return On Assets -0.22349001
Return On Equity -0.89653
Revenue Growth -0.703
Revenue Per Share 0.035
Sand P52 Week Change 0.38150132
Sector Healthcare
Sector Disp Healthcare
Sector Key healthcare
Shares Outstanding 101,773,573
Shares Percent Shares Out 0.0291
Shares Short 2,964,467
Shares Short Previous Month Date 1,772,150,400
Shares Short Prior Month 3,316,141
Short Name AC Immune SA
Short Percent Of Float 0.060700003
Short Ratio 11.21
Source Interval 15
Symbol ACIU
Target High Price 12.10449
Target Low Price 7.0141153
Target Mean Price 9.117328
Target Median Price 8.675353
Total Cash 91,412,000
Total Cash Per Share 0.921
Total Debt 4,541,000
Total Revenue 3,573,000
Tradeable 0
Trailing Annual Dividend Rate 0.0
Trailing Annual Dividend Yield 0.0
Trailing Eps -0.9
Trailing Peg Ratio None
Triggerable 1
Two Hundred Day Average 2.8539
Two Hundred Day Average Change 0.15610003
Two Hundred Day Average Change Percent 0.054697093
Type Disp Equity
Volume 265,057
Website https://www.acimmune.com
Zip 1,015