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Acumen Pharmaceuticals, Inc. (ABOS)

Healthcare | Biotechnology | Newton, United States | NasdaqGS
2.64 USD +0.01 (0.380%) ⇧ (July 13, 2026, 4 p.m. EDT)
After hours: 2.65 +0.01 (0.379%) ⇧ (July 13, 2026, 5:18 p.m. EDT)

Short-term:★★☆☆☆Long-term:★☆☆☆☆Dividends:☆☆☆☆☆
Hot Take | July 11, 2026, 4:29 a.m. EDT

The investment case for Acumen Pharmaceuticals is severely compromised by a catastrophic multi-year decline. Over the last four years, the stock has lost 92.43% of its value, driven by three consecutive years of negative annual performance. While the company holds a fortress-like balance sheet with a current ratio of 4.55 and manageable debt relative to cash, these strengths are irrelevant in a biotech sector where capital preservation is paramount without proven product revenue. The business is burning cash, with free cash flow of -$67 million and negative returns on equity, signaling that the current asset base is eroding value rather than generating it. The options market confirms this pessimism, with traders buying deep protection at strikes far above the current price while ignoring upside potential. Although the forward P/E is technically negative due to losses, this is not a value opportunity; it is a reflection of a company that has failed to execute its growth thesis over a sustained period. The recent price action shows some volatility, but the structural damage to shareholder value is too severe to recommend a long-term entry.

Model Selection — Backtest MAE (log-scale, lower is better)
ModelMAE
MSTL_126 ✓0.060143
AutoTheta0.077404
AutoETS0.092141
AutoARIMA0.092146
MSTL0.094123
MSTL_74_1260.102662
MSTL_740.155783

Forecast horizon: 60 days | Selected: MSTL_126

Forecast Reliability
Score 35%
H-stat 1.49
Ljung-Box p 0.000
Jarque-Bera p 0.377
Excess Kurtosis -0.85
Attribute Value
Sector Healthcare
Debt to Equity Ratio 35.622
Market Cap 190,680,832
Forward P/E -1.75
Beta 0.34
Website https://acumenpharm.com

As of July 11, 2026, 4:29 a.m. EDT: Speculators are positioning aggressively for downside protection, evidenced by heavy put volume and open interest at the $5.00 strike compared to negligible call activity. Implied volatility is significantly elevated for out-of-the-money puts (12.88%) versus calls (3.28%), indicating a market expectation of a sharp drop rather than a rally. The lack of call open interest above the current price suggests a 'bear put spread' or hedging strategy is dominant.


Info Dump

Attribute Value
52 Week Change 0.7651007
Address1 1,210-1220 Washington St.
Address2 Suite 210
All Time High 26.98
All Time Low 0.855
Ask 3.31
Ask Size 2
Audit Risk 9
Average Daily Volume10 Day 924,560
Average Daily Volume3 Month 443,009
Average Volume 443,009
Average Volume10Days 924,560
Beta 0.341
Bid 1.95
Bid Size 2
Board Risk 6
Book Value 1.211
City Newton
Compensation As Of Epoch Date 1,767,139,200
Compensation Risk 8
Country United States
Crypto Tradeable 0
Currency USD
Current Price 2.64
Current Ratio 4.553
Custom Price Alert Confidence HIGH
Date Short Interest 1,782,777,600
Day High 2.72
Day Low 2.57
Debt To Equity 35.622
Display Name Acumen Pharmaceuticals
Earnings Call Timestamp End 1,778,587,200
Earnings Call Timestamp Start 1,778,587,200
Earnings Timestamp 1,778,589,000
Earnings Timestamp End 1,786,451,400
Earnings Timestamp Start 1,786,451,400
Ebitda -114,556,000
Ebitda Margins 0.0
Enterprise To Ebitda -0.816
Enterprise Value 93,443,808
Eps Current Year -1.58455
Eps Forward -1.50668
Eps Trailing Twelve Months -1.85
Esg Populated 0
Exchange NMS
Exchange Data Delayed By 0
Exchange Timezone Name America/New_York
Exchange Timezone Short Name EDT
Fifty Day Average 2.4314
Fifty Day Average Change 0.20860004
Fifty Day Average Change Percent 0.08579421
Fifty Two Week Change Percent 76.51007
Fifty Two Week High 3.6
Fifty Two Week High Change -0.9599998
Fifty Two Week High Change Percent -0.26666662
Fifty Two Week Low 1.19
Fifty Two Week Low Change 1.45
Fifty Two Week Low Change Percent 1.2184874
Fifty Two Week Range 1.19 - 3.6
Financial Currency USD
First Trade Date Milliseconds 1,625,146,200,000
Float Shares 36,955,964
Forward Eps -1.50668
Forward P E -1.7521969
Free Cashflow -67,432,624
Full Exchange Name NasdaqGS
Full Time Employees 60
Gmt Off Set Milliseconds -14,400,000
Governance Epoch Date 1,782,864,000
Gross Margins 0.0
Gross Profits -104,933,000
Has Pre Post Market Data 1
Held Percent Insiders 0.06801
Held Percent Institutions 0.64157
Implied Shares Outstanding 72,227,580
Industry Biotechnology
Industry Disp Biotechnology
Industry Key biotechnology
Ipo Expected Date 2,021-07-01
Is Earnings Date Estimate 1
Language en-US
Last Fiscal Year End 1,767,139,200
Long Business Summary Acumen Pharmaceuticals, Inc., a clinical-stage biopharmaceutical company, develops targeted therapies for the treatment of Alzheimer's disease. It focuses on advancing a targeted immunotherapy drug candidate, sabirnetug (ACU193), which is in its Phase 2 ALTITUDE-AD clinical trial to target toxic soluble amyloid beta oligomers. Acumen Pharmaceuticals, Inc. has a collaboration and license agreement with Halozyme, Inc. for the development of a subcutaneous formulation of Sabirnetug, as well as with JCR Pharmaceuticals Co. Ltd for the development of Aß oligomer-targeted enhanced brain delivery therapy for the treatment of Alzheimer's disease. The company was incorporated in 1996 and is headquartered in Newton, Massachusetts.
Long Name Acumen Pharmaceuticals, Inc.
Market us_market
Market Cap 190,680,832
Market State POSTPOST
Max Age 86,400
Message Board Id finmb_8539521
Most Recent Quarter 1,774,915,200
Net Income To Common -113,276,000
Next Fiscal Year End 1,798,675,200
Non Diluted Market Cap 189,958,535
Number Of Analyst Opinions 5
Open 2.59
Operating Cashflow -105,545,000
Operating Margins 0.0
Overall Risk 7
Payout Ratio 0.0
Phone 617 344 4190
Post Market Change 0.00999999
Post Market Change Percent 0.3787875
Post Market Price 2.65
Post Market Time 1,783,977,516
Previous Close 2.63
Price Eps Current Year -1.6660882
Price Hint 4
Price To Book 2.1800168
Profit Margins 0.0
Quick Ratio 4.43
Quote Source Name Nasdaq Real Time Price
Quote Type EQUITY
Recommendation Key none
Region US
Regular Market Change 0.00999999
Regular Market Change Percent 0.380228
Regular Market Day High 2.72
Regular Market Day Low 2.57
Regular Market Day Range 2.57 - 2.72
Regular Market Open 2.59
Regular Market Previous Close 2.63
Regular Market Price 2.64
Regular Market Time 1,783,972,801
Regular Market Volume 406,254
Return On Assets -0.42372
Return On Equity -0.93232
Sand P52 Week Change 0.20847368
Sector Healthcare
Sector Disp Healthcare
Sector Key healthcare
Share Holder Rights Risk 8
Shares Outstanding 72,227,580
Shares Percent Shares Out 0.038599998
Shares Short 2,788,975
Shares Short Previous Month Date 1,780,012,800
Shares Short Prior Month 1,892,556
Short Name Acumen Pharmaceuticals, Inc.
Short Percent Of Float 0.0554
Short Ratio 4.07
Source Interval 15
State MA
Symbol ABOS
Target High Price 10.0
Target Low Price 4.0
Target Mean Price 7.4
Target Median Price 8.0
Total Cash 128,398,000
Total Cash Per Share 1.778
Total Debt 31,161,000
Tradeable 0
Trailing Annual Dividend Rate 0.0
Trailing Annual Dividend Yield 0.0
Trailing Eps -1.85
Trailing Peg Ratio None
Triggerable 1
Two Hundred Day Average 2.315225
Two Hundred Day Average Change 0.32477522
Two Hundred Day Average Change Percent 0.14027804
Type Disp Equity
Volume 406,254
Website https://acumenpharm.com
Zip 2,465