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Acumen Pharmaceuticals, Inc. (ABOS)

Healthcare | Biotechnology | Newton, United States | NasdaqGS
1.82 USD -0.20 (-10.149%) ⇩ (Oct. 13, 2026, 4 p.m. EDT)
After hours: 1.83 +0.01 (0.826%) ⇧ (Oct. 13, 2026, 4:23 p.m. EDT)

Short-term:★☆☆☆☆Long-term:⯪☆☆☆☆Dividends:☆☆☆☆☆
Hot Take ↕ | Oct. 10, 2026, 6:32 a.m. EDT

The investment case for Acumen Pharmaceuticals is currently broken by a catastrophic multi-year decline and deteriorating fundamentals. The stock has lost over 83% of its value over the last four years, with every single year in that window posting negative returns. This is not a temporary correction; it is a structural failure where the market has repeatedly rejected the company's value proposition. Fundamentally, the business is bleeding cash with negative free cash flow, negative operating cash flow, and a return on equity of -120%. The balance sheet, while technically liquid, supports a company that is burning through capital without generating revenue or profit. Analyst consensus is a 'strong buy' with a target price of $7.60, but this ignores the reality that the stock trades at a forward P/E of negative infinity because earnings are deeply negative. The options market confirms this pessimism, with traders aggressively buying puts and selling calls at strikes far above the current price, betting on further collapse. There is no catalyst visible in the data to reverse this trend, making this a dangerous speculative vehicle rather than an investment opportunity.

Model Selection — Backtest MAE (log-scale, lower is better)
ModelMAE
MSTL ✓0.181985
AutoETS0.195410
AutoTheta0.195647
AutoARIMA0.195798

Forecast horizon: 45 days | Selected: MSTL

Forecast Reliability
Score 33%
H-stat 9.76
Ljung-Box p 0.000
Jarque-Bera p 0.178
Excess Kurtosis -1.34
Attribute Value
Sector Healthcare
Debt to Equity Ratio 55.264
Market Cap 131,255,880
Forward P/E -1.27
Beta 0.33
Website https://acumenpharm.com

As of Oct. 10, 2026, 6:32 a.m. EDT: Speculators are overwhelmingly positioning for downside protection rather than upside participation. Put open interest significantly exceeds call open interest across all expirations, with heavy concentration in out-of-the-money strikes (e.g., $5.00 puts showing new volume flow exceeding existing open interest). Call activity is negligible, limited mostly to ATM anchors, while put writers are accumulating significant exposure at strikes far above the current price, indicating a strong consensus expectation of further decline.


Info Dump

Attribute Value
52 Week Change -0.13304722
Address1 1,210-1220 Washington St.
Address2 Suite 210
All Time High 26.98
All Time Low 0.855
Ask 2.35
Ask Size 2
Audit Risk 9
Average Analyst Rating 1.0 - Strong Buy
Average Daily Volume10 Day 703,690
Average Daily Volume3 Month 437,896
Average Volume 437,896
Average Volume10Days 703,690
Beta 0.332
Bid 1.44
Bid Size 2
Board Risk 6
Book Value 0.792
City Newton
Compensation As Of Epoch Date 1,767,139,200
Compensation Risk 8
Country United States
Crypto Tradeable 0
Currency USD
Current Price 1.815
Current Ratio 2.466
Custom Price Alert Confidence HIGH
Date Short Interest 1,790,726,400
Day High 2.0
Day Low 1.81
Debt To Equity 55.264
Display Name Acumen Pharmaceuticals
Dividend Yield 0.0
Earnings Call Timestamp End 1,786,536,000
Earnings Call Timestamp Start 1,786,536,000
Earnings Timestamp 1,786,537,800
Earnings Timestamp End 1,794,400,200
Earnings Timestamp Start 1,794,400,200
Ebitda -105,367,000
Ebitda Margins 0.0
Enterprise To Ebitda -0.641
Enterprise Value 67,529,912
Eps Current Year -1.5891
Eps Forward -1.43278
Eps Trailing Twelve Months -1.64
Esg Populated 0
Exchange NMS
Exchange Data Delayed By 15
Exchange Timezone Name America/New_York
Exchange Timezone Short Name EDT
Fifty Day Average 2.5976
Fifty Day Average Change -0.7825999
Fifty Day Average Change Percent -0.30127808
Fifty Two Week Change Percent -13.304722
Fifty Two Week High 3.6
Fifty Two Week High Change -1.7849998
Fifty Two Week High Change Percent -0.4958333
Fifty Two Week Low 1.5
Fifty Two Week Low Change 0.31500006
Fifty Two Week Low Change Percent 0.21000004
Fifty Two Week Range 1.5 - 3.6
Financial Currency USD
First Trade Date Milliseconds 1,625,146,200,000
Float Shares 37,045,976
Forward Eps -1.43278
Forward P E -1.2667681
Free Cashflow -56,503,376
Full Exchange Name NasdaqGS
Full Time Employees 60
Fullday Change -0.18999994
Fullday Change Percent -9.405938
Fullday Price 1.83
Gmt Off Set Milliseconds -14,400,000
Governance Epoch Date 1,790,812,800
Gross Margins 0.0
Gross Profits -86,787,000
Has Pre Post Market Data 1
Held Percent Insiders 0.067930005
Held Percent Institutions 0.66592
Implied Shares Outstanding 72,317,285
Industry Biotechnology
Industry Disp Biotechnology
Industry Key biotechnology
Ipo Expected Date 2,021-07-01
Is Earnings Date Estimate 0
Language en-US
Last Fiscal Year End 1,767,139,200
Long Business Summary Acumen Pharmaceuticals, Inc., a clinical-stage biopharmaceutical company, develops targeted therapies for the treatment of Alzheimer's disease. It focuses on advancing a targeted immunotherapy drug candidate, sabirnetug (ACU193), which is in its Phase 2 ALTITUDE-AD clinical trial to target toxic soluble amyloid beta oligomers. Acumen Pharmaceuticals, Inc. has a collaboration and license agreement with Halozyme, Inc. for the development of a subcutaneous formulation of Sabirnetug, as well as with JCR Pharmaceuticals Co. Ltd for the development of Aß oligomer-targeted enhanced brain delivery therapy for the treatment of Alzheimer's disease. The company was incorporated in 1996 and is headquartered in Newton, Massachusetts.
Long Name Acumen Pharmaceuticals, Inc.
Market us_market
Market Cap 131,255,880
Market State POST
Max Age 86,400
Message Board Id finmb_8539521
Most Recent Quarter 1,782,777,600
Net Income To Common -105,044,000
Next Fiscal Year End 1,798,675,200
Non Diluted Market Cap 166,691,341
Number Of Analyst Opinions 5
Open 2.0
Operating Cashflow -91,788,000
Operating Margins 0.0
Overall Risk 7
Payout Ratio 0.0
Phone 617 344 4190
Post Market Change 0.014999986
Post Market Change Percent 0.82644546
Post Market Price 1.83
Post Market Time 1,791,923,006
Previous Close 2.02
Price Eps Current Year -1.142156
Price Hint 4
Price To Book 2.2916667
Profit Margins 0.0
Quick Ratio 2.379
Quote Source Name Nasdaq Real Time Price
Quote Type EQUITY
Recommendation Key strong_buy
Recommendation Mean 1.0
Region US
Regular Market Change -0.20499992
Regular Market Change Percent -10.148511
Regular Market Day High 2.0
Regular Market Day Low 1.81
Regular Market Day Range 1.81 - 2.0
Regular Market Open 2.0
Regular Market Previous Close 2.02
Regular Market Price 1.815
Regular Market Time 1,791,921,601
Regular Market Volume 645,309
Return On Assets -0.45769
Return On Equity -1.20505
Sand P52 Week Change 0.17502642
Sector Healthcare
Sector Disp Healthcare
Sector Key healthcare
Share Holder Rights Risk 8
Shares Outstanding 72,317,285
Shares Percent Shares Out 0.042600002
Shares Short 3,079,512
Shares Short Previous Month Date 1,788,134,400
Shares Short Prior Month 3,163,185
Short Name Acumen Pharmaceuticals, Inc.
Short Percent Of Float 0.061100002
Short Ratio 6.26
Source Interval 15
State MA
Symbol ABOS
Target High Price 10.0
Target Low Price 5.0
Target Mean Price 7.6
Target Median Price 8.0
Total Cash 110,197,000
Total Cash Per Share 1.524
Total Debt 31,646,000
Tradeable 0
Trailing Annual Dividend Rate 0.0
Trailing Annual Dividend Yield 0.0
Trailing Eps -1.64
Trailing Peg Ratio None
Triggerable 1
Two Hundred Day Average 2.506575
Two Hundred Day Average Change -0.69157505
Two Hundred Day Average Change Percent -0.2759044
Type Disp Equity
Volume 645,309
Website https://acumenpharm.com
Zip 2,465